| Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system A Koussounadis, SP Langdon, IH Um, DJ Harrison, VA Smith Scientific reports 5 (1), 10775, 2015 | 693 | 2015 |
| Antitumor Activity and Pharmacokinetics in Mice of 8-Carbamoyl-3-methyl-imidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (CCRG 81045; M & B 39831), a Novel Drug … MFG Stevens, JA Hickman, SP Langdon, D Chubb, L Vickers, R Stone, ... Cancer research 47 (22), 5846-5852, 1987 | 548 | 1987 |
| Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer SA Eccles, EO Aboagye, S Ali, AS Anderson, J Armes, F Berditchevski, ... Breast Cancer Research 15, 1-37, 2013 | 517 | 2013 |
| Functional restoration of BRCA2 protein by secondary BRCA2 mutations in BRCA2-mutated ovarian carcinoma W Sakai, EM Swisher, C Jacquemont, KV Chandramohan, FJ Couch, ... Cancer research 69 (16), 6381-6386, 2009 | 357 | 2009 |
| Characterization and properties of nine human ovarian adenocarcinoma cell lines SP Langdon, SS Lawrie, FG Hay, MM Hawkes, A McDonald, IP Hayward, ... Cancer research 48 (21), 6166-6172, 1988 | 311 | 1988 |
| The prognostic value of epidermal growth factor receptor mRNA expression in primary ovarian cancer JMS Bartlett, SP Langdon, BJB Simpson, M Stewart, D Katsaros, ... British journal of cancer 73 (3), 301-306, 1996 | 261 | 1996 |
| Quantitative analysis of changes in ER, PR and HER2 expression in primary breast cancer and paired nodal metastases SJ Aitken, JS Thomas, SP Langdon, DJ Harrison, D Faratian Annals of Oncology 21 (6), 1254-1261, 2010 | 252 | 2010 |
| Antiestrogen therapy is active in selected ovarian cancer cases: the use of letrozole in estrogen receptor–positive patients JF Smyth, C Gourley, G Walker, MJ MacKean, A Stevenson, ... Clinical Cancer Research 13 (12), 3617-3622, 2007 | 237 | 2007 |
| New strategies for targeting the hypoxic tumour microenvironment in breast cancer C Ward, SP Langdon, P Mullen, AL Harris, DJ Harrison, CT Supuran, ... Cancer treatment reviews 39 (2), 171-179, 2013 | 228 | 2013 |
| CA125 response is associated with estrogen receptor expression in a phase II trial of letrozole in ovarian cancer: identification of an endocrine-sensitive subgroup A Bowman, H Gabra, SP Langdon, A Lessells, M Stewart, A Young, ... Clinical cancer research 8 (7), 2233-2239, 2002 | 210 | 2002 |
| Estrogen receptor-α mediates gene expression changes and growth response in ovarian cancer cells exposed to estrogen AJM O’Donnell, KG Macleod, DJ Burns, JF Smyth, SP Langdon Endocrine-related cancer 12 (4), 851-866, 2005 | 198 | 2005 |
| Systems biology reveals new strategies for personalizing cancer medicine and confirms the role of PTEN in resistance to trastuzumab D Faratian, A Goltsov, G Lebedeva, A Sorokin, S Moodie, P Mullen, C Kay, ... Cancer research 69 (16), 6713-6720, 2009 | 197 | 2009 |
| Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma SL Cooke, CKY Ng, N Melnyk, MJ Garcia, T Hardcastle, J Temple, ... Oncogene 29 (35), 4905-4913, 2010 | 196 | 2010 |
| Growth of Small Cell Lung Cancer Cells: Stimulation by Multiple Neuropeptides and Inhibition by Broad Spectrum Antagonists in Vitro and in Vivo T Sethi, S Langdon, J Smyth, E Rozengurt Cancer Research 52 (9_Supplement), 2737s-2742s, 1992 | 186 | 1992 |
| A comparative analysis of inhibitors of the glycolysis pathway in breast and ovarian cancer cell line models C Xintaropoulou, C Ward, A Wise, H Marston, A Turnbull, SP Langdon Oncotarget 6 (28), 25677, 2015 | 185 | 2015 |
| Altered ErbB receptor signaling and gene expression in cisplatin-resistant ovarian cancer K Macleod, P Mullen, J Sewell, G Rabiasz, S Lawrie, E Miller, JF Smyth, ... Cancer research 65 (15), 6789-6800, 2005 | 174 | 2005 |
| Expression of the heat shock protein HSP27 in human ovarian cancer. SP Langdon, GJ Rabiasz, GL Hirst, RJ King, RA Hawkins, JF Smyth, ... Clinical cancer research: an official journal of the American Association …, 1995 | 174 | 1995 |
| Cancer cell culture SP Langdon Humana 5 (9), 2010 | 171 | 2010 |
| High antitumour activity of ET743 against human tumour xenografts from melanoma, non-small-cell lung and ovarian cancer HR Hendriks, HH Fiebig, R Giavazzi, SP Langdon, JM Jimeno, ... Annals of Oncology 10 (10), 1233-1240, 1999 | 145 | 1999 |
| Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium EO Pettersen, P Ebbesen, RG Gieling, KJ Williams, L Dubois, P Lambin, ... Journal of enzyme inhibition and medicinal chemistry 30 (5), 689-721, 2015 | 133 | 2015 |
David J HarrisonUniversity of St AndrewsVerified email at nucana.com
