Nada Lallous
Nada Lallous
Assistant Professor, University of British Columbia
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Functional analysis of androgen receptor mutations that confer anti-androgen resistance identified in circulating cell-free DNA from prostate cancer patients
N Lallous, SV Volik, S Awrey, E Leblanc, R Tse, J Murillo, K Singh, ...
Genome Biology 17 (10), 2016
Targeting alternative sites on the androgen receptor to treat castration-resistant prostate cancer
N Lallous, K Dalal, A Cherkasov, PS Rennie
International journal of molecular sciences 14 (6), 12496-12519, 2013
Identification of a potent antiandrogen that targets the BF3 site of the androgen receptor and inhibits enzalutamide-resistant prostate cancer
RSN Munuganti, MDH Hassona, E Leblanc, K Frewin, K Singh, D Ma, ...
Chemistry & biology 21 (11), 1476-1485, 2014
Moving towards precision urologic oncology: targeting enzalutamide-resistant prostate cancer and mutated forms of the androgen receptor using the novel inhibitor darolutamide …
H Borgmann, N Lallous, D Ozistanbullu, E Beraldi, N Paul, K Dalal, L Fazli, ...
European Urology 73 (1), 4-8, 2018
Structure, functional characterization, and evolution of the dihydroorotase domain of human CAD
A Grande-García, N Lallous, C Díaz-Tejada, S Ramón-Maiques
Structure 22 (2), 185-198, 2014
The PHD finger of human UHRF1 reveals a new subgroup of unmethylated histone H3 tail readers
N Lallous, P Legrand, AG McEwen, S Ramón-Maiques, JP Samama, ...
PloS one 6 (11), e27599, 2011
An oncofetal glycosaminoglycan modification provides therapeutic access to cisplatin-resistant bladder cancer
R Seiler, HZ Oo, D Tortora, TM Clausen, CK Wang, G Kumar, MA Pereira, ...
European urology 72 (1), 142-150, 2017
Androgen receptor plasticity and its implications for prostate cancer therapy
O Snow, N Lallous, K Singh, N Lack, P Rennie, A Cherkasov
Cancer Treatment Reviews 81, 101871, 2019
Ivermectin inhibits HSP27 and potentiates efficacy of oncogene targeting in tumor models
L Nappi, AH Aguda, N Al Nakouzi, B Lelj-Garolla, E Beraldi, N Lallous, ...
The Journal of clinical investigation 130 (2), 699-714, 2020
Androgen receptor-binding sites are highly mutated in prostate cancer
T Morova, DR McNeill, N Lallous, M Gönen, K Dalal, DM Wilson, A Gürsoy, ...
Nature communications 11 (1), 1-10, 2020
Computer-aided drug discovery of Myc-Max inhibitors as potential therapeutics for prostate cancer
LA Carabet, N Lallous, E Leblanc, F Ban, H Morin, S Lawn, F Ghaidi, ...
European journal of medicinal chemistry 160, 108-119, 2018
Bypassing Drug Resistance Mechanisms of Prostate Cancer with Small Molecules that Target Androgen Receptor–Chromatin InteractionsTargeting Androgen Receptor Interactions with …
K Dalal, M Che, NS Que, A Sharma, R Yang, N Lallous, H Borgmann, ...
Molecular cancer therapeutics 16 (10), 2281-2291, 2017
In silico discovery and validation of potent small-molecule inhibitors targeting the activation function 2 site of human oestrogen receptor α
K Singh, RSN Munuganti, E Leblanc, YL Lin, E Leung, N Lallous, M Butler, ...
Breast Cancer Research 17 (1), 1-17, 2015
Computer-aided discovery of small molecules targeting the RNA splicing activity of hnRNP A1 in castration-resistant prostate cancer
LA Carabet, E Leblanc, N Lallous, H Morin, F Ghaidi, J Lee, PS Rennie, ...
Molecules 24 (4), 763, 2019
Targeting binding function-3 of the androgen receptor blocks its co-chaperone interactions, nuclear translocation, and activation
N Lallous, E Leblanc, RSN Munuganti, MDH Hassona, NA Nakouzi, ...
Molecular cancer therapeutics 15 (12), 2936-2945, 2016
Discovery of new catalytic topoisomerase II inhibitors for anticancer therapeutics
VM Matias-Barrios, M Radaeva, Y Song, Z Alperstein, AR Lee, V Schmitt, ...
Frontiers in oncology, 3293, 2021
Expression, purification, crystallization and preliminary X-ray diffraction analysis of the aspartate transcarbamoylase domain of human CAD
A Ruiz-Ramos, N Lallous, A Grande-García, S Ramón-Maiques
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013
Cheminformatics Modeling of Adverse Drug Responses by Clinically Relevant Mutants of Human Androgen Receptor
AC Naman Paul, Lavinia Arielle Carabet, Nada Lallous, Takeshi Yamazaki ...
Journal of Chemical Information and Modeling, 2016
Expression, purification, crystallization and preliminary X-ray diffraction analysis of the dihydroorotase domain of human CAD
N Lallous, A Grande-García, R Molina, S Ramón-Maiques
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2012
Expression, purification, crystallization and preliminary crystallographic study of the SRA domain of the human UHRF1 protein
B Delagoutte, N Lallous, C Birck, P Oudet, JP Samama
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2008
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