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Johan van Heerden
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Lost in Transition: Startup of Glycolysis Yields Subpopulations of Nongrowing Cells
JH van Heerden, MT Wortel, FJ Bruggeman, JJ Heijnen, YJM Bollen, ...
Science, 1245114, 2014
3092014
Taking chances and making mistakes: non-genetic phenotypic heterogeneity and its consequences for surviving in dynamic environments
C van Boxtel, JH van Heerden, N Nordholt, P Schmidt, FJ Bruggeman
Journal of The Royal Society Interface 14 (132), 20170141, 2017
1002017
Whole-cell modeling in yeast predicts compartment-specific proteome constraints that drive metabolic strategies
IE Elsemman, A Rodriguez Prado, P Grigaitis, M Garcia Albornoz, ...
Nature communications 13 (1), 1-12, 2022
562022
Statistics and simulation of growth of single bacterial cells: illustrations with B. subtilis and E. coli
JH Heerden, H Kempe, A Doerr, T Maarleveld, N Nordholt, FJ Bruggeman
Scientific reports 7 (16094), 2017
522017
Parallel changes in gene expression in peripheral blood mononuclear cells and the brain after maternal separation in the mouse
JH van Heerden, A Conesa, DJ Stein, D Montaner, V Russell, N Illing
BMC research notes 2 (1), 1-10, 2009
492009
Effects of growth rate and promoter activity on single-cell protein expression
N Nordholt, J van Heerden, R Kort, FJ Bruggeman
Scientific Reports 7 (6299), 2017
412017
Multi‐tasking of biosynthetic and energetic functions of glycolysis explained by supply and demand logic
JH van Heerden, FJ Bruggeman, B Teusink
BioEssays 37 (1), 34-45, 2015
402015
Biphasic cell-size and growth-rate homeostasis by single Bacillus subtilis cells
N Nordholt, JH van Heerden, FJ Bruggeman
Current Biology 30 (12), 2238-2247. e5, 2020
372020
Evaluating the behavioural consequences of early maternal separation in adult C57BL/6 mice; the importance of time
JH van Heerden, V Russell, A Korff, DJ Stein, N Illing
Behavioural brain research 207 (2), 332-342, 2010
342010
Structural and biochemical characterization of a nitrilase from the thermophilic bacterium, Geobacillus pallidus RAPc8
DS Williamson, KC Dent, BW Weber, A Varsani, J Frederick, RN Thuku, ...
Applied microbiology and biotechnology 88 (1), 143-153, 2010
312010
An improved ATP FRET sensor for yeast shows heterogeneity during nutrient transitions
D Botman, JH van Heerden, B Teusink
ACS sensors 5 (3), 814-822, 2020
272020
Metabolism at Evolutionary Optimal States
I Rabbers, JH van Heerden, N Nordholt, H Bachmann, B Teusink, ...
Metabolites 5 (2), 311-343, 2015
172015
A yeast FRET biosensor enlightens cAMP signaling
D Botman, TG O’Toole, J Goedhart, FJ Bruggeman, JH van Heerden, ...
Molecular Biology of the Cell 32 (13), 1229-1240, 2021
152021
Fatal attraction in glycolysis: how Saccharomyces cerevisiae manages sudden transitions to high glucose
JH van Heerden, MT Wortel, FJ Bruggeman, JJ Heijnen, Y JM
Microbial Cell 1 (3), 103-106, 2014
102014
pH dependencies of glycolytic enzymes of yeast under in vivo‐like assay conditions
L Luzia, D Lao‐Martil, P Savakis, J van Heerden, N van Riel, B Teusink
The FEBS Journal, 2022
92022
Serial propagation in water-in-oil emulsions selects for Saccharomyces cerevisiae strains with a reduced cell size or an increased biomass yield on glucose
RJ van Tatenhove-Pel, E Zwering, DF Boreel, M Falk, JH van Heerden, ...
Metabolic Engineering 64, 1-14, 2021
92021
A computational toolbox to investigate the metabolic potential and resource allocation in fission yeast
P Grigaitis, DAJ Grundel, E van Pelt-KleinJan, M Isaku, G Xie, SM Farias, ...
mSystems, 2022
22022
A framework for the informed normalization of printed microarrays
J Van Heerden, SA Walford, A Shen, N Illing
South African Journal of Science 103 (9), 381-390, 2007
22007
Growth consequences of the inhomogeneous organization of the bacterial cytoplasm
JH van Heerden, AM Berkvens, DH de Groot, FJ Bruggeman
bioRxiv, 2023.04. 18.537336, 2023
12023
Integrated biphasic growth rate, gene expression, and cell-size homeostasis behaviour of single B. subtilis cells
N Nordholt, JH van Heerden, FJ Bruggeman
bioRxiv, 510925, 2019
12019
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Articles 1–20