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Allison M Keeler
Allison M Keeler
Assistant Professor
Verified email at umassmed.edu - Homepage
Title
Cited by
Cited by
Year
Recombinant adeno-associated virus gene therapy in light of Luxturna (and Zolgensma and Glybera): where are we, and how did we get here?
AM Keeler, TR Flotte
Annual review of virology 6, 601-621, 2019
2642019
Gene therapy 2017: progress and future directions
AM Keeler, MK ElMallah, TR Flotte
Clinical and translational science 10 (4), 242, 2017
1782017
Lack of Cystic Fibrosis Transmembrane Conductance Regulator in CD3+ Lymphocytes Leads to Aberrant Cytokine Secretion and Hyperinflammatory Adaptive …
C Mueller, SA Braag, A Keeler, C Hodges, M Drumm, TR Flotte
American journal of respiratory cell and molecular biology 44 (6), 922-929, 2011
1462011
Widespread central nervous system gene transfer and silencing after systemic delivery of novel AAV-AS vector
SR Choudhury, AF Harris, DJ Cabral, AM Keeler, E Sapp, JS Ferreira, ...
Molecular Therapy 24 (4), 726-735, 2016
1332016
Systemic AAV9 gene transfer in adult GM1 gangliosidosis mice reduces lysosomal storage in CNS and extends lifespan
CM Weismann, J Ferreira, AM Keeler, Q Su, L Qui, SA Shaffer, Z Xu, ...
Human molecular genetics 24 (15), 4353-4364, 2015
1022015
CAR T-cell therapy: progress and prospects
O Wilkins, AM Keeler, TR Flotte
Human gene therapy methods 28 (2), 61-66, 2017
772017
AAV gene therapy for Tay-Sachs disease
TR Flotte, O Cataltepe, A Puri, AR Batista, R Moser, D McKenna-Yasek, ...
Nature medicine 28 (2), 251-259, 2022
552022
Death after high-dose rAAV9 gene therapy in a patient with Duchenne’s muscular dystrophy
A Lek, B Wong, A Keeler, M Blackwood, K Ma, S Huang, K Sylvia, ...
New England Journal of Medicine 389 (13), 1203-1210, 2023
402023
CAR-T regulatory (CAR-Treg) cells: engineering and applications
M Arjomandnejad, AL Kopec, AM Keeler
Biomedicines 10 (2), 287, 2022
362022
Cellular analysis of silencing the Huntington’s disease gene using AAV9 mediated delivery of artificial micro RNA into the striatum of Q140/Q140 mice
AM Keeler, E Sapp, K Chase, E Sottosanti, E Danielson, E Pfister, ...
Journal of Huntington's disease 5 (3), 239-248, 2016
362016
Systemic Delivery of AAVB1-GAA Clears Glycogen and Prolongs Survival in a Mouse Model of Pompe Disease
AM Keeler, M Zieger, SH Todeasa, AL McCall, JC Gifford, S Birsak, ...
Human Gene Therapy 30 (1), 57-68, 2019
352019
Long-term correction of very long-chain acyl-coA dehydrogenase deficiency in mice using AAV9 gene therapy
AM Keeler, T Conlon, G Walter, H Zeng, SA Shaffer, F Dungtao, K Erger, ...
Molecular Therapy 20 (6), 1131-1138, 2012
342012
CRISPR/Cas-Dependent and Nuclease-Free In Vivo Therapeutic Gene Editing
I Dasgupta, TR Flotte, AM Keeler
Human gene therapy 32 (5-6), 275-293, 2021
322021
Immunogenicity of recombinant adeno-associated virus (AAV) vectors for gene transfer
M Arjomandnejad, I Dasgupta, TR Flotte, AM Keeler
BioDrugs 37 (3), 311-329, 2023
242023
Intralingual and intrapleural AAV gene therapy prolongs survival in a SOD1 ALS mouse model
AM Keeler, M Zieger, C Semple, L Pucci, A Veinbachs, RH Brown, ...
Molecular Therapy-Methods & Clinical Development 17, 246-257, 2020
242020
Airway smooth muscle dysfunction in Pompe (Gaa−/−) mice
AM Keeler, D Liu, M Zieger, L Xiong, J Salemi, K Bellvé, BJ Byrne, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 312 (6 …, 2017
232017
Modulating immune responses to AAV by expanded polyclonal T-regs and capsid specific chimeric antigen receptor T-regulatory cells
M Arjomandnejad, K Sylvia, M Blackwood, T Nixon, Q Tang, M Muhuri, ...
Molecular Therapy Methods & Clinical Development 23, 490-506, 2021
222021
Cell and gene therapy for genetic diseases: inherited disorders affecting the lung and those mimicking sudden infant death syndrome
AM Keeler, TR Flotte
Human gene therapy 23 (6), 548-556, 2012
202012
Unexpected death of a Duchenne muscular dystrophy patient in an N-of-1 trial of rAAV9-delivered CRISPR-transactivator
A Lek, B Wong, A Keeler, M Blackwood, K Ma, S Huang, K Sylvia, ...
MedRxiv, 2023.05. 16.23289881, 2023
162023
Novel combinatorial microRNA-binding sites in AAV vectors synergistically diminish antigen presentation and transgene immunity for efficient and stable transduction
M Muhuri, W Zhan, Y Maeda, A Lotun, I Dasgupta, M Arjomandnejad, ...
Frontiers in Immunology 12, 674242, 2021
162021
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