| Germline NLRP1 mutations cause skin inflammatory and cancer susceptibility syndromes via inflammasome activation FL Zhong, O Mamaï, L Sborgi, L Boussofara, R Hopkins, K Robinson, ... Cell 167 (1), 187-202. e17, 2016 | 391 | 2016 |
| First report of Mycobacterium bovis DNA in human remains from the Iron Age GM Taylor, E Murphy, R Hopkins, P Rutland, Y Chistov Microbiology 153 (4), 1243-1249, 2007 | 229 | 2007 |
| Human DPP9 represses NLRP1 inflammasome and protects against autoinflammatory diseases via both peptidase activity and FIIND domain binding FL Zhong, K Robinson, DET Teo, KY Tan, C Lim, CR Harapas, CH Yu, ... Journal of Biological Chemistry 293 (49), 18864-18878, 2018 | 191 | 2018 |
| B cell TLR7 expression drives anti-RNA autoantibody production and exacerbates disease in systemic lupus erythematosus–prone mice SH Hwang, H Lee, M Yamamoto, LA Jones, J Dayalan, R Hopkins, ... The Journal of Immunology 189 (12), 5786-5796, 2012 | 119 | 2012 |
| Met-Flow, a strategy for single-cell metabolic analysis highlights dynamic changes in immune subpopulations PJ Ahl, RA Hopkins, WW Xiang, B Au, N Kaliaperumal, AM Fairhurst, ... Communications biology 3 (1), 305, 2020 | 110 | 2020 |
| RNA sensing by conventional dendritic cells is central to the development of lupus nephritis T Celhar, R Hopkins, SI Thornhill, R De Magalhaes, SH Hwang, HY Lee, ... Proceedings of the National Academy of Sciences 112 (45), E6195-E6204, 2015 | 52 | 2015 |
| The specialized roles of immature and mature dendritic cells in antigen cross-presentation RA Hopkins, JE Connolly Immunologic research 53, 91-107, 2012 | 51 | 2012 |
| Tuberculosis among Iron Age individuals from Tyva, South Siberia: palaeopathological and biomolecular findings EM Murphy, YK Chistov, R Hopkins, P Rutland, GM Taylor Journal of Archaeological Science 36 (9), 2029-2038, 2009 | 47 | 2009 |
| Dual neonate vaccine platform against HIV-1 and M. tuberculosis R Hopkins, A Bridgeman, J Joseph, SC Gilbert, H McShane, T Hanke PloS one 6 (5), e20067, 2011 | 43 | 2011 |
| Optimizing HIV‐1‐specific CD8+ T‐cell induction by recombinant BCG in prime‐boost regimens with heterologous viral vectors R Hopkins, A Bridgeman, C Bourne, A Mbewe‐Mvula, JC Sadoff, ... European journal of immunology 41 (12), 3542-3552, 2011 | 34 | 2011 |
| Novel Recombinant Mycobacterium bovis BCG, Ovine Atadenovirus, and Modified Vaccinia Virus Ankara Vaccines Combine To Induce Robust Human … M Rosario, R Hopkins, J Fulkerson, N Borthwick, MF Quigley, J Joseph, ... Journal of virology 84 (12), 5898-5908, 2010 | 32 | 2010 |
| Ovine atadenovirus, a novel and highly immunogenic vector in prime-boost studies of a candidate HIV-1 vaccine A Bridgeman, Y Roshorm, LJ Lockett, ZZ Xu, R Hopkins, J Shaw, GW Both, ... Vaccine 28 (2), 474-483, 2009 | 32 | 2009 |
| Dominant-negative NFKBIA mutation promotes IL-1β production causing hepatic disease with severe immunodeficiency EEK Tan, RA Hopkins, CK Lim, SS Jamuar, C Ong, KC Thoon, MJA Koh, ... The Journal of Clinical Investigation 130 (11), 5817-5832, 2020 | 20 | 2020 |
| A perspective on cell therapy and cancer vaccine in biliary tract cancers (BTCs) S Han, SY Lee, WW Wang, YB Tan, RHZ Sim, R Cheong, C Tan, ... Cancers 12 (11), 3404, 2020 | 19 | 2020 |
| Monocytic myeloid-derived suppressor cells underpin resistance to adoptive T cell therapy in nasopharyngeal carcinoma R Hopkins, W Xiang, D Marlier, VB Au, Q Ching, LX Wu, R Guan, B Lee, ... Molecular Therapy 29 (2), 734-743, 2021 | 14 | 2021 |
| A phase I study of an adenoviral vector delivering a MUC1/CD40-ligand fusion protein in patients with advanced adenocarcinoma TJ Tan, WXG Ang, WW Wang, HS Chong, SH Tan, R Cheong, JWK Chia, ... Nature Communications 13 (1), 6453, 2022 | 10 | 2022 |
| First-in-man study of Ad-sig-hMUC1/ecdCD40L vaccine for immunotherapy of MUC1 overexpressing epithelial cancers. TJY Tan, JWK Chia, HS Chong, X Li, SH Tan, R Hopkins, WW Wang, ... Journal of Clinical Oncology 36 (15_suppl), 3098-3098, 2018 | 5 | 2018 |
| A novel GPI-anchored dominant-negative TGF-β receptor II renders T cells unresponsive to TGF-β signaling SH Petersen, K Al Badawy, R Hopkins, DL Vu, M Rahmani, SMP Maia, ... Molecular Therapy-Oncolytics 31, 2023 | 3 | 2023 |
| Cellular immune biomarkers to prognosticate for survival to adoptive T-cell therapy in advanced nasopharyngeal cancer. HC Toh, R Hopkins, QT Ching, VB Au, LX Wu, WK Chia, B Lee, WW Wang, ... Journal of Clinical Oncology 35 (15_suppl), 6047-6047, 2017 | 2 | 2017 |
| DPP9 is an endogenous and direct inhibitor of the NLRP1 inflammasome that guards against human auto-inflammatory diseases FL Zhong, K Robinson, C Lim, CR Harapas, CH Yu, W Xie, RM Sobota, ... bioRxiv, 260919, 2018 | 1 | 2018 |
Tomas HankeProfessor of Vaccine Immunology, University of OxfordVerified email at ndm.ox.ac.uk
