Joshua D Hutcheson
Joshua D Hutcheson
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Genesis and growth of extracellular-vesicle-derived microcalcification in atherosclerotic plaques
JD Hutcheson, C Goettsch, S Bertazzo, N Maldonado, JL Ruiz, W Goh, ...
Nature materials 15 (3), 335-343, 2016
Adventitial MSC-like cells are progenitors of vascular smooth muscle cells and drive vascular calcification in chronic kidney disease
R Kramann, C Goettsch, J Wongboonsin, H Iwata, RK Schneider, ...
Cell stem cell 19 (5), 628-642, 2016
Serotonin receptors and heart valve disease—it was meant 2B
JD Hutcheson, V Setola, BL Roth, WD Merryman
Pharmacology & therapeutics 132 (2), 146-157, 2011
Sortilin mediates vascular calcification via its recruitment into extracellular vesicles
C Goettsch, JD Hutcheson, M Aikawa, H Iwata, T Pham, A Nykjaer, ...
The Journal of clinical investigation 126 (4), 1323-1336, 2016
Spatiotemporal multi-omics mapping generates a molecular atlas of the aortic valve and reveals networks driving disease
F Schlotter, A Halu, S Goto, MC Blaser, SC Body, LH Lee, H Higashi, ...
Circulation 138 (4), 377-393, 2018
Valvular interstitial cells suppress calcification of valvular endothelial cells
J Hjortnaes, K Shapero, C Goettsch, JD Hutcheson, J Keegan, J Kluin, ...
Atherosclerosis 242 (1), 251-260, 2015
Potential drug targets for calcific aortic valve disease
JD Hutcheson, E Aikawa, WD Merryman
Nature Reviews Cardiology 11 (4), 218-231, 2014
An electrically active microneedle array for electroporation
SO Choi, YC Kim, JH Park, J Hutcheson, HS Gill, YK Yoon, MR Prausnitz, ...
Biomedical microdevices 12, 263-273, 2010
Small entities with large impact: microcalcifications and atherosclerotic plaque vulnerability
JD Hutcheson, N Maldonado, E Aikawa
Current opinion in lipidology 25 (5), 327, 2014
Extracellular vesicles as mediators of cardiovascular calcification
A Bakhshian Nik, JD Hutcheson, E Aikawa
Frontiers in cardiovascular medicine 4, 78, 2017
A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification
C Goettsch, JD Hutcheson, S Hagita, MA Rogers, MD Creager, T Pham, ...
Atherosclerosis 251, 109-118, 2016
Cadherin-11 regulates cell–cell tension necessary for calcific nodule formation by valvular myofibroblasts
JD Hutcheson, J Chen, MK Sewell-Loftin, LM Ryzhova, CI Fisher, YR Su, ...
Arteriosclerosis, thrombosis, and vascular biology 33 (1), 114-120, 2013
5-HT2B antagonism arrests non-canonical TGF-β1-induced valvular myofibroblast differentiation
JD Hutcheson, LM Ryzhova, V Setola, WD Merryman
Journal of molecular and cellular cardiology 53 (5), 707-714, 2012
MicroRNA in cardiovascular calcification: focus on targets and extracellular vesicle delivery mechanisms
C Goettsch, JD Hutcheson, E Aikawa
Circulation research 112 (7), 1073-1084, 2013
Extracellular vesicles in cardiovascular calcification: expanding current paradigms
JB Krohn, JD Hutcheson, E Martínez‐Martínez, E Aikawa
The Journal of physiology 594 (11), 2895-2903, 2016
18F-Fluoride Signal Amplification Identifies Microcalcifications Associated With Atherosclerotic Plaque Instability in Positron Emission Tomography/Computed …
MD Creager, T Hohl, JD Hutcheson, AJ Moss, F Schlotter, MC Blaser, ...
Circulation: Cardiovascular Imaging 12 (1), e007835, 2019
Cardiovascular calcification: current controversies and novel concepts
JL Ruiz, JD Hutcheson, E Aikawa
Cardiovascular Pathology 24 (4), 207-212, 2015
Dynamin-related protein 1 inhibition attenuates cardiovascular calcification in the presence of oxidative stress
MA Rogers, N Maldonado, JD Hutcheson, C Goettsch, S Goto, I Yamada, ...
Circulation research 121 (3), 220-233, 2017
Directing valvular interstitial cell myofibroblast‐like differentiation in a hybrid hydrogel platform
J Hjortnaes, G Camci‐Unal, JD Hutcheson, SM Jung, FJ Schoen, J Kluin, ...
Advanced healthcare materials 4 (1), 121-130, 2015
Simulation of early calcific aortic valve disease in a 3D platform: a role for myofibroblast differentiation
J Hjortnaes, C Goettsch, JD Hutcheson, G Camci-Unal, L Lax, K Scherer, ...
Journal of molecular and cellular cardiology 94, 13-20, 2016
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