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Justin Deme
Justin Deme
National Cancer Institute
Verified email at nih.gov
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Cited by
Year
Structure of the core of the type III secretion system export apparatus
L Kuhlen, P Abrusci, S Johnson, J Gault, J Deme, J Caesar, T Dietsche, ...
Nature structural & molecular biology 25 (7), 583-590, 2018
1752018
Type 9 secretion system structures reveal a new protein transport mechanism
F Lauber, JC Deme, SM Lea, BC Berks
Nature 564 (7734), 77-82, 2018
1492018
Structures of the stator complex that drives rotation of the bacterial flagellum
JC Deme, S Johnson, O Vickery, A Aron, H Monkhouse, T Griffiths, ...
Nature Microbiology 5 (12), 1553-1564, 2020
1392020
Molecular basis for redox control by the human cystine/glutamate antiporter system xc
JL Parker, JC Deme, D Kolokouris, G Kuteyi, PC Biggin, SM Lea, ...
Nature communications 12 (1), 7147, 2021
852021
Molecular structure of the intact bacterial flagellar basal body
S Johnson, EJ Furlong, JC Deme, AL Nord, JJE Caesar, FFV Chevance, ...
Nature microbiology 6 (6), 712-721, 2021
642021
Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation
S Johnson, YH Fong, JC Deme, EJ Furlong, L Kuhlen, SM Lea
Nature Microbiology 5 (7), 966-975, 2020
622020
The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion
L Kuhlen, S Johnson, A Zeitler, S Bäurle, JC Deme, JJE Caesar, R Debo, ...
Nature communications 11 (1), 1296, 2020
612020
The structure of an injectisome export gate demonstrates conservation of architecture in the core export gate between flagellar and virulence type III secretion systems
S Johnson, L Kuhlen, JC Deme, P Abrusci, SM Lea
MBio 10 (3), 10.1128/mbio. 00818-19, 2019
542019
Structure and mechanism of the proton-driven motor that powers type 9 secretion and gliding motility
R Hennell James, JC Deme, A Kjӕr, F Alcock, A Silale, F Lauber, ...
Nature microbiology 6 (2), 221-233, 2021
532021
Structural basis of antifolate recognition and transport by PCFT
JL Parker, JC Deme, G Kuteyi, Z Wu, J Huo, ID Goldman, RJ Owens, ...
Nature 595 (7865), 130-134, 2021
482021
Mechanism of lipid droplet formation by the yeast Sei1/Ldb16 Seipin complex
YA Klug, JC Deme, RA Corey, MF Renne, PJ Stansfeld, SM Lea, ...
Nature communications 12 (1), 5892, 2021
462021
Purification and interaction analyses of two human lysosomal vitamin B12 transporters: LMBD1 and ABCD4
JC Deme, MA Hancock, X Xia, CA Shintre, M Plesa, JC Kim, ...
Molecular membrane biology 31 (7-8), 250-261, 2014
432014
SIMPLE 3.0. Stream single-particle cryo-EM analysis in real time
J Caesar, CF Reboul, C Machello, S Kiesewetter, ML Tang, JC Deme, ...
Journal of structural biology: X 4, 100040, 2020
422020
Cryo-EM structure of PepT2 reveals structural basis for proton-coupled peptide and prodrug transport in mammals
JL Parker, JC Deme, Z Wu, G Kuteyi, J Huo, RJ Owens, PC Biggin, ...
Science advances 7 (35), eabh3355, 2021
352021
Subcellular location of MMACHC and MMADHC, two human proteins central to intracellular vitamin B12 metabolism
W Mah, JC Deme, D Watkins, S Fung, A Janer, EA Shoubridge, ...
Molecular genetics and metabolism 108 (2), 112-118, 2013
352013
Cryo-EM structure and resistance landscape of M. tuberculosis MmpL3: An emergent therapeutic target
O Adams, JC Deme, JL Parker, PW Fowler, SM Lea, S Newstead
Structure 29 (10), 1182-1191. e4, 2021
332021
A signal sequence suppressor mutant that stabilizes an assembled state of the twin arginine translocase
Q Huang, F Alcock, H Kneuper, JC Deme, SE Rollauer, SM Lea, BC Berks, ...
Proceedings of the National Academy of Sciences 114 (10), E1958-E1967, 2017
312017
Structural features of recombinant MMADHC isoforms and their interactions with MMACHC, proteins of mammalian vitamin B12 metabolism
JC Deme, IR Miousse, M Plesa, JC Kim, MA Hancock, W Mah, ...
Molecular genetics and metabolism 107 (3), 352-362, 2012
312012
Membrane Protein Complex ExbB4-ExbD1-TonB1 from Escherichia coli Demonstrates Conformational Plasticity
A Sverzhinsky, JW Chung, JC Deme, L Fabre, KT Levey, M Plesa, ...
Journal of bacteriology 197 (11), 1873-1885, 2015
272015
Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1
RJ Harding, JC Deme, JF Hevler, S Tamara, A Lemak, JP Cantle, ...
Communications Biology 4 (1), 1374, 2021
262021
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