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Sylvan Baca MD PhD
Sylvan Baca MD PhD
Assistant Professor, Harvard Medical School
Verified email at partners.org - Homepage
Title
Cited by
Cited by
Year
Mutational heterogeneity in cancer and the search for new cancer-associated genes
MS Lawrence, P Stojanov, P Polak, GV Kryukov, K Cibulskis, ...
Nature 499 (7457), 214-218, 2013
57752013
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer
CE Barbieri, SC Baca, MS Lawrence, F Demichelis, M Blattner, ...
Nature genetics 44 (6), 685-689, 2012
17342012
Punctuated evolution of prostate cancer genomes
SC Baca, D Prandi, MS Lawrence, JM Mosquera, A Romanel, Y Drier, ...
Cell 153 (3), 666-677, 2013
14062013
Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma
JA Perry, A Kiezun, P Tonzi, EM Van Allen, SL Carter, SC Baca, ...
Proceedings of the National Academy of Sciences 111 (51), E5564-E5573, 2014
4312014
Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis
AM Dulak, SE Schumacher, J Van Lieshout, Y Imamura, C Fox, B Shim, ...
Cancer research 72 (17), 4383-4393, 2012
3052012
Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer
JPP Theurillat, ND Udeshi, WJ Errington, T Svinkina, SC Baca, M Pop, ...
Science 346 (6205), 85-89, 2014
2362014
Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes
PV Nuzzo, JE Berchuck, K Korthauer, S Spisak, AH Nassar, S Abou Alaiwi, ...
Nature medicine 26 (7), 1041-1043, 2020
2072020
Prostate cancer reactivates developmental epigenomic programs during metastatic progression
MM Pomerantz, X Qiu, Y Zhu, DY Takeda, W Pan, SC Baca, A Gusev, ...
Nature genetics 52 (8), 790-799, 2020
1842020
EZH2 inhibition activates a dsRNA–STING–interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer
KL Morel, AV Sheahan, DL Burkhart, SC Baca, N Boufaied, Y Liu, X Qiu, ...
Nature cancer 2 (4), 444-456, 2021
1402021
Unraveling the clonal hierarchy of somatic genomic aberrations
D Prandi, SC Baca, A Romanel, CE Barbieri, JM Mosquera, J Fontugne, ...
Genome biology 15, 1-16, 2014
1042014
Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma
Z Bakouny, DA Braun, SA Shukla, W Pan, X Gao, Y Hou, A Flaifel, S Tang, ...
Nature communications 12 (1), 808, 2021
1002021
CDK7 inhibition suppresses castration-resistant prostate cancer through MED1 inactivation
R Rasool, R Natesan, Q Deng, S Aras, P Lal, S Sander Effron, ...
Cancer discovery 9 (11), 1538-1555, 2019
942019
Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer
SC Baca, DY Takeda, JH Seo, J Hwang, SY Ku, R Arafeh, T Arnoff, ...
Nature communications 12 (1), 1979, 2021
902021
Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer
P Cejas, Y Xie, A Font-Tello, K Lim, S Syamala, X Qiu, AK Tewari, N Shah, ...
Nature communications 12 (1), 5775, 2021
762021
Qualifiers of atypia in the cytologic diagnosis of thyroid nodules are associated with different Afirma gene expression classifier results and clinical outcomes
SC Baca, KS Wong, KC Strickland, HT Heller, MI Kim, JA Barletta, ...
Cancer Cytopathology 125 (5), 313-322, 2017
692017
Mammalian SWI/SNF complex genomic alterations and immune checkpoint blockade in solid tumors
S Abou Alaiwi, AH Nassar, W Xie, Z Bakouny, JE Berchuck, DA Braun, ...
Cancer immunology research 8 (8), 1075-1084, 2020
612020
The genomic landscape of prostate cancer
SC Baca, LA Garraway
Frontiers in endocrinology 3, 69, 2012
572012
HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer
X Lu, K Fong, G Gritsina, F Wang, SC Baca, LT Brea, JE Berchuck, ...
Nature genetics 54 (5), 670-683, 2022
492022
ASCL1 activates neuronal stem cell-like lineage programming through remodeling of the chromatin landscape in prostate cancer
S Nouruzi, D Ganguli, N Tabrizian, M Kobelev, O Sivak, T Namekawa, ...
Nature Communications 13 (1), 2282, 2022
462022
H3K27ac HiChIP in prostate cell lines identifies risk genes for prostate cancer susceptibility
C Giambartolomei, JH Seo, T Schwarz, MK Freund, RD Johnson, ...
The American Journal of Human Genetics 108 (12), 2284-2300, 2021
362021
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