| Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase JF Couture, E Collazo, PA Ortiz-Tello, JS Brunzelle, RC Trievel Nature structural & molecular biology 14 (8), 689-695, 2007 | 301 | 2007 |
| The functional diversity of protein lysine methylation S Lanouette, V Mongeon, D Figeys, JF Couture Molecular systems biology 10 (4), 724, 2014 | 294 | 2014 |
| Molecular recognition of histone H3 by the WD40 protein WDR5 JF Couture, E Collazo, RC Trievel Nature structural & molecular biology 13 (8), 698-703, 2006 | 280 | 2006 |
| Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase JF Couture, E Collazo, JS Brunzelle, RC Trievel Genes & development 19 (12), 1455-1465, 2005 | 261 | 2005 |
| Structural basis for the methylation site specificity of SET7/9 JF Couture, E Collazo, G Hauk, RC Trievel Nature structural & molecular biology 13 (2), 140-146, 2006 | 189 | 2006 |
| Selective methylation of histone H3 variant H3. 1 regulates heterochromatin replication Y Jacob, E Bergamin, MTA Donoghue, V Mongeon, C LeBlanc, P Voigt, ... Science 343 (6176), 1249-1253, 2014 | 171 | 2014 |
| Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5 G Senisterra, H Wu, A Allali-Hassani, GA Wasney, D Barsyte-Lovejoy, ... Biochemical Journal 449 (1), 151-159, 2013 | 162 | 2013 |
| A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy M Chitiprolu, C Jagow, V Tremblay, E Bondy-Chorney, G Paris, A Savard, ... Nature communications 9 (1), 2794, 2018 | 153 | 2018 |
| Structure and regulon of Campylobacter jejuni ferric uptake regulator Fur define apo-Fur regulation J Butcher, S Sarvan, JS Brunzelle, JF Couture, A Stintzi Proceedings of the National Academy of Sciences 109 (25), 10047-10052, 2012 | 145 | 2012 |
| Proteomic analyses of the SMYD family interactomes identify HSP90 as a novel target for SMYD2 M Abu-Farha, S Lanouette, F Elisma, V Tremblay, J Butson, D Figeys, ... Journal of molecular cell biology 3 (5), 301-308, 2011 | 141 | 2011 |
| Structural origins for the product specificity of SET domain protein methyltransferases JF Couture, LMA Dirk, JS Brunzelle, RL Houtz, RC Trievel Proceedings of the National Academy of Sciences 105 (52), 20659-20664, 2008 | 132 | 2008 |
| A coupled fluorescent assay for histone methyltransferases E Collazo, JF Couture, S Bulfer, RC Trievel Analytical biochemistry 342 (1), 86-92, 2005 | 132 | 2005 |
| UTX inhibition as selective epigenetic therapy against TAL1-driven T-cell acute lymphoblastic leukemia A Benyoucef, CG Palii, C Wang, CJ Porter, A Chu, F Dai, V Tremblay, ... Genes & development 30 (5), 508-521, 2016 | 124 | 2016 |
| Structural and biochemical insights into MLL1 core complex assembly V Avdic, P Zhang, S Lanouette, A Groulx, V Tremblay, J Brunzelle, ... Structure 19 (1), 101-108, 2011 | 121 | 2011 |
| The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases P Zhang, H Lee, JS Brunzelle, JF Couture Nucleic acids research 40 (9), 4237-4246, 2012 | 117 | 2012 |
| Histone-modifying enzymes: encrypting an enigmatic epigenetic code JF Couture, RC Trievel Current opinion in structural biology 16 (6), 753-760, 2006 | 111 | 2006 |
| Catalytic roles for carbon-oxygen hydrogen bonding in SET domain lysine methyltransferases JF Couture, G Hauk, MJ Thompson, GM Blackburn, RC Trievel Journal of Biological Chemistry 281 (28), 19280-19287, 2006 | 105 | 2006 |
| Binding of RNA by APOBEC3G controls deamination-independent restriction of retroviruses K Belanger, M Savoie, MC Rosales Gerpe, JF Couture, MA Langlois Nucleic acids research 41 (15), 7438-7452, 2013 | 99 | 2013 |
| Structure and conformational dynamics of a COMPASS histone H3K4 methyltransferase complex Q Qu, Y Takahashi, Y Yang, H Hu, Y Zhang, JS Brunzelle, JF Couture, ... Cell 174 (5), 1117-1126. e12, 2018 | 96 | 2018 |
| Structural characterization of the human androgen receptor ligand-binding domain complexed with EM5744, a rationally designed steroidal ligand bearing a bulky chain directed … L Cantin, F Faucher, JF Couture, KP de Jésus-Tran, P Legrand, ... Journal of biological chemistry 282 (42), 30910-30919, 2007 | 82 | 2007 |
