| Tricyclic dihydrobenzoxazepine and tetracyclic indole derivatives can specifically target bacterial DNA ligases and can distinguish them from human DNA ligase I N Yadav, T Khanam, A Shukla, N Rai, K Hajela, R Ramachandran Organic & biomolecular chemistry 13 (19), 5475-5487, 2015 | 21 | 2015 |
| Structural-functional diversity of malaria parasite’s PfHSP70-1 and PfHSP40 chaperone pair gives an edge over human orthologs in chaperone-assisted protein folding. M Anas, A Shukla, A Tripathi, V Kumari, C Prakash, P Nag, LS Kumar, ... BIOCHEMICAL JOURNAL, 2020 | 11 | 2020 |
| M. tuberculosis class II apurinic/ apyrimidinic‐endonuclease/3′‐5′ exonuclease (XthA) engages with NAD+-dependent DNA ligase A (LigA) to counter futile … T Khanam, M Afsar, A Shukla, F Alam, S Kumar, H Soyar, K Dolma, ... Nucleic acids research 48 (8), 4325-4343, 2020 | 7 | 2020 |
| Membrane insertion mechanism of the caveola coat protein Cavin1 KC Liu, H Pace, E Larsson, S Hossain, A Kabedev, A Shukla, ... Proceedings of the National Academy of Sciences 119 (25), e2202295119, 2022 | 5 | 2022 |
| Critical determinants for substrate recognition and catalysis in the M. tuberculosis class II AP-endonuclease/3′–5′ exonuclease III T Khanam, A Shukla, N Rai, R Ramachandran Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1854 (5), 505-516, 2015 | 5 | 2015 |
| Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer M Afsar, GQ Liu, L Jia, EA Ruben, D Nayak, Z Sayyad, PS Bury, KE Cano, ... Nature communications 14 (1), 4786, 2023 | 2 | 2023 |
| Structure based identification of first-in-class fragment inhibitors that target the NMN pocket of M. tuberculosis NAD+-dependent DNA ligase A A Shukla, M Afsar, N Kumar, S Kumar, R Ramachandran Journal of structural biology 213 (1), 107655, 2021 | 2 | 2021 |
| Regulation of futile ligation during early steps of BER in M. tuberculosis is carried out by a β-clamp-XthA-LigA tri-component complex A Shukla, M Afsar, T Khanam, N Kumar, F Ali, S Kumar, F Jahan, ... International Journal of Biological Macromolecules 225, 442-453, 2023 | 1 | 2023 |
| Salt bridges at the subdomain interfaces of the adenylation domain and active-site residues of Mycobacterium tuberculosis NAD + -dependent DNA ligase A (MtbLigA) are important … M Afsar, A Shukla, R Ramachandran Acta Cryst D, 776–789, 2021 | | 2021 |
| M . t u b e rc u l o s i s class II apurinic/ apyrimidinic-endonuclease/3?-5? exonuclease (XthA) engages with NAD+-dependent DNA ligase A (LigA) to counter futile cleavage and … * Taran Khanam1,†, Mohammad Afsar1,†, Ankita Shukla1,†, Faiyaz Alam 2 ... Nucleic Acids Research, 2020 | | 2020 |
| Supplementary information for ‘Important determinants for substrate recognition and catalysis in the M. tuberculosis class II AP-endonuclease/3'-5'exonuclease III’ T Khanam, A Shukla, N Rai, R Ramachandran | | |
