| Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress R Ghosh, L Wang, ES Wang, BGK Perera, A Igbaria, S Morita, K Prado, ... Cell 158 (3), 534-548, 2014 | 467 | 2014 |
| Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors L Wang, BGK Perera, SB Hari, B Bhhatarai, BJ Backes, MA Seeliger, ... Nature chemical biology 8 (12), 982-989, 2012 | 228 | 2012 |
| Prediction of aqueous solubility, vapor pressure and critical micelle concentration for aquatic partitioning of perfluorinated chemicals B Bhhatarai, P Gramatica Environmental science & technology 45 (19), 8120-8128, 2011 | 169 | 2011 |
| CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity K Mansouri, N Kleinstreuer, AM Abdelaziz, D Alberga, VM Alves, ... Environmental Health Perspectives 128 (2), 027002, 2020 | 137 | 2020 |
| Opportunities and challenges using artificial intelligence in ADME/Tox B Bhhatarai, WP Walters, CECA Hop, G Lanza, S Ekins Nature materials 18 (5), 418, 2019 | 93 | 2019 |
| The activities of drug inactive ingredients on biological targets J Pottel, D Armstrong, L Zou, A Fekete, XP Huang, H Torosyan, ... Science 369 (6502), 403-413, 2020 | 69 | 2020 |
| Alternative approaches for identifying acute systemic toxicity: Moving from research to regulatory testing J Hamm, K Sullivan, AJ Clippinger, J Strickland, S Bell, B Bhhatarai, ... Toxicology in Vitro 41, 245-259, 2017 | 67 | 2017 |
| Novel selective allosteric and bitopic ligands for the S1P3 receptor E Jo, B Bhhatarai, E Repetto, M Guerrero, S Riley, SJ Brown, Y Kohno, ... ACS chemical biology 7 (12), 1975-1983, 2012 | 66 | 2012 |
| A sphingosine 1-phosphate receptor 2 selective allosteric agonist H Satsu, MT Schaeffer, M Guerrero, A Saldana, C Eberhart, P Hodder, ... Bioorganic & medicinal chemistry 21 (17), 5373-5382, 2013 | 65 | 2013 |
| Evaluation of TOPKAT, Toxtree, and Derek Nexus in Silico Models for Ocular Irritation and Development of a Knowledge-Based Framework To Improve the Prediction of Severe Irritation B Bhhatarai, DM Wilson, AK Parks, EW Carney, PJ Spencer Chemical research in toxicology, 2016 | 54 | 2016 |
| Per-and Polyfluoro Toxicity (LC50 Inhalation) Study in Rat and Mouse Using QSAR Modeling B Bhhatarai, P Gramatica Chemical research in toxicology 23 (3), 528-539, 2010 | 50 | 2010 |
| GPCR ontology: development and application of a G protein-coupled receptor pharmacology knowledge framework MJ Przydzial, B Bhhatarai, A Koleti, U Vempati, SC Schürer Bioinformatics 29 (24), 3211-3219, 2013 | 41 | 2013 |
| Modelling physico-chemical properties of (benzo) triazoles, and screening for environmental partitioning B Bhhatarai, P Gramatica Water research 45 (3), 1463-1471, 2011 | 41 | 2011 |
| Oral LD50 toxicity modeling and prediction of per-and polyfluorinated chemicals on rat and mouse B Bhhatarai, P Gramatica Molecular diversity 15 (2), 467-476, 2011 | 38 | 2011 |
| CADASTER QSPR Models for Predictions of Melting and Boiling Points of Perfluorinated Chemicals B Bhhatarai, W Teetz, T Liu, T Öberg, N Jeliazkova, N Kochev, O Pukalov, ... Molecular Informatics 30 (2‐3), 189-204, 2011 | 36 | 2011 |
| From SAR to comparative QSAR: role of hydrophobicity in the design of 4-hydroxy-5, 6-dihydropyran-2-ones HIV-1 protease inhibitors B Bhhatarai, R Garg Bioorganic & medicinal chemistry 13 (12), 4078-4084, 2005 | 31 | 2005 |
| Evaluation of OASIS QSAR Models Using ToxCast in Vitro Estrogen and Androgen Receptor Binding Data and Application in an Integrated Endocrine Screening Approach B Bhhatarai, DM Wilson, PS Price, S Marty, AK Parks, E Carney Environmental health perspectives, 2016 | 26 | 2016 |
| A mechanistic study of 3-aminoindazole cyclic urea HIV-1 protease inhibitors using comparative QSAR R Garg, B Bhhatarai Bioorganic & medicinal chemistry 12 (22), 5819-5831, 2004 | 26 | 2004 |
| Acute toxicity prediction in multiple species by leveraging mechanistic ToxCast mitochondrial inhibition data and simulation of oral bioavailability B Bhhatarai, DM Wilson, MJ Bartels, S Chaudhuri, PS Price, EW Carney Toxicological Sciences 147 (2), 386-396, 2015 | 23 | 2015 |
| Performance evaluation of the GastroPlusTM software tool for prediction of the toxicokinetic parameters of chemicals F Zhang, M Bartels, A Clark, T Erskine, T Auernhammer, B Bhhatarai, ... SAR and QSAR in Environmental Research 29 (11), 875-893, 2018 | 15 | 2018 |
Paola GramaticaFull Professor of Environmental Chemistry, Senior Prof.,Insubria University, Varese, ItalyVerified email at uninsubria.it
