| Systematic screening of all signal peptides from Bacillus subtilis: a powerful strategy in optimizing heterologous protein secretion in Gram-positive bacteria U Brockmeier, M Caspers, R Freudl, A Jockwer, T Noll, T Eggert Journal of molecular biology 362 (3), 393-402, 2006 | 315 | 2006 |
| The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer R Sewell, M Bäckström, M Dalziel, S Gschmeissner, H Karlsson, T Noll, ... Journal of Biological Chemistry 281 (6), 3586-3594, 2006 | 264 | 2006 |
| The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9 R Beatson, V Tajadura-Ortega, D Achkova, G Picco, TD Tsourouktsoglou, ... Nature immunology 17 (11), 1273-1281, 2016 | 234 | 2016 |
| Adult palatum as a novel source of neural crest-related stem cells D Widera, C Zander, M Heidbreder, Y Kasperek, T Noll, O Seitz, ... Stem cells 27 (8), 1899-1910, 2009 | 182 | 2009 |
| Chinese hamster genome sequenced from sorted chromosomes K Brinkrolf, O Rupp, H Laux, F Kollin, W Ernst, B Linke, R Kofler, ... Nature biotechnology 31 (8), 694-695, 2013 | 178 | 2013 |
| Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing J Becker, M Hackl, O Rupp, T Jakobi, J Schneider, R Szczepanowski, ... Journal of biotechnology 156 (3), 227-235, 2011 | 119 | 2011 |
| Recombinant MUC1 mucin with a breast cancer-like O-glycosylation produced in large amounts in Chinese-hamster ovary cells M Bäckström, T Link, FJ Olson, H Karlsson, R Graham, G Picco, J Burchell, ... Biochemical Journal 376 (3), 677-686, 2003 | 109 | 2003 |
| Quantitative characterization of metabolism and metabolic shifts during growth of the new human cell line AGE1. HN using time resolved metabolic flux analysis J Niklas, E Schräder, V Sandig, T Noll, E Heinzle Bioprocess and biosystems engineering 34, 533-545, 2011 | 106 | 2011 |
| Recombinant tumor-associated MUC1 glycoprotein impairs the differentiation and function of dendritic cells A Rughetti, I Pellicciotta, M Biffoni, M Bäckström, T Link, EP Bennet, ... The journal of Immunology 174 (12), 7764-7772, 2005 | 96 | 2005 |
| Methods in mammalian cell line engineering: from random mutagenesis to sequence-specific approaches O Krämer, S Klausing, T Noll Applied microbiology and biotechnology 88, 425-436, 2010 | 92 | 2010 |
| Bioprocess development for the production of a recombinant MUC1 fusion protein expressed by CHO-K1 cells in protein-free medium T Link, M Bäckström, R Graham, R Essers, K Zörner, J Gätgens, J Burchell, ... Journal of Biotechnology 110 (1), 51-62, 2004 | 91 | 2004 |
| Dielectric spectroscopy in the cultivation of suspended and immobilized hybridoma cells T Noll, M Biselli Journal of biotechnology 63 (3), 187-198, 1998 | 79 | 1998 |
| Construction of a public CHO cell line transcript database using versatile bioinformatics analysis pipelines O Rupp, J Becker, K Brinkrolf, C Timmermann, N Borth, A Pühler, T Noll, ... PloS one 9 (1), e85568, 2014 | 76 | 2014 |
| Effects of high passage cultivation on CHO cells: a global analysis TF Beckmann, O Krämer, S Klausing, C Heinrich, T Thüte, H Büntemeyer, ... Applied microbiology and biotechnology 94, 659-671, 2012 | 70 | 2012 |
| Primary cells as feeder cells for coculture expansion of human hematopoietic stem cells from umbilical cord blood—a comparative study AS Magin, NR Körfer, H Partenheimer, C Lange, A Zander, T Noll Stem Cells and Development 18 (1), 173-186, 2009 | 63 | 2009 |
| Engineered and natural promoters and chromatin‐modifying elements for recombinant protein expression in CHO cells N Romanova, T Noll Biotechnology Journal 13 (3), 1700232, 2018 | 58 | 2018 |
| Utilization and evaluation of CHO‐specific sequence databases for mass spectrometry based proteomics P Meleady, R Hoffrogge, M Henry, O Rupp, JH Bort, C Clarke, K Brinkrolf, ... Biotechnology and bioengineering 109 (6), 1386-1394, 2012 | 57 | 2012 |
| Computational identification of microRNA gene loci and precursor microRNA sequences in CHO cell lines M Hackl, V Jadhav, T Jakobi, O Rupp, K Brinkrolf, A Goesmann, A Pühler, ... Journal of Biotechnology 158 (3), 151-155, 2012 | 57 | 2012 |
| Cultivation of hematopoietic stem and progenitor cells: biochemical engineering aspects T Noll, N Jelinek, S Schmidt, M Biselli, C Wandrey Tools and Applications of Biochemical Engineering Science, 111-128, 2002 | 54 | 2002 |
| How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology? MJT Carrondo, PM Alves, N Carinhas, J Glassey, F Hesse, OW Merten, ... Biotechnology Journal 7 (12), 1522-1529, 2012 | 52 | 2012 |
Alexander GrünbergerMultiscale Bioengineering, Faculty of Technology, Bielefeld UniversityVerified email at uni-bielefeld.de
