Standardization of real-time PCR gene expression data from independent biological replicates E Willems, L Leyns, J Vandesompele Analytical biochemistry 379 (1), 127-129, 2008 | 528 | 2008 |
The need for transparency and good practices in the qPCR literature SA Bustin, V Benes, J Garson, J Hellemans, J Huggett, M Kubista, ... Nature methods 10 (11), 1063-1067, 2013 | 308 | 2013 |
Small-Molecule Inhibitors of the Wnt Pathway Potently Promote Cardiomyocytes From Human Embryonic Stem Cell–Derived Mesoderm E Willems, S Spiering, H Davidovics, M Lanier, Z Xia, M Dawson, ... Circulation research 109 (4), 360-364, 2011 | 287 | 2011 |
Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development C Kemp, E Willems, S Abdo, L Lambiv, L Leyns Developmental dynamics: an official publication of the American Association …, 2005 | 268 | 2005 |
Selection of reference genes in mouse embryos and in differentiating human and mouse ES cells. E Willems, I Mateizel, C Kemp, G Cauffman, K Sermon, L Leyns International Journal of Developmental Biology 50 (7), 2006 | 153 | 2006 |
Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells E Willems, J Cabral-Teixeira, D Schade, W Cai, P Reeves, PJ Bushway, ... Cell stem cell 11 (2), 242-252, 2012 | 144 | 2012 |
Induced pluripotent stem cells in cardiovascular drug discovery M Mercola, A Colas, E Willems Circulation research 112 (3), 534-548, 2013 | 135 | 2013 |
Wnt3a binds to several sFRPs in the nanomolar range D Wawrzak, M Métioui, E Willems, M Hendrickx, E De Genst, L Leyns Biochemical and biophysical research communications 357 (4), 1119-1123, 2007 | 122 | 2007 |
Hepatic natural killer cells exclusively kill splenic/blood natural killer-resistant tumor cells by the perforin/granzyme pathway D Vermijlen, D Luo, CJ Froelich, JP Medema, JA Kummer, E Willems, ... Journal of leukocyte biology 72 (4), 668-676, 2002 | 122 | 2002 |
Expression of Frizzled5, Frizzled7, and Frizzled10 during early mouse development and interactions with canonical Wnt signaling CR Kemp, E Willems, D Wawrzak, M Hendrickx, T Agbor Agbor, L Leyns Developmental dynamics: an official publication of the American Association …, 2007 | 95 | 2007 |
An optimized procedure for whole-mount in situ hybridization on mouse embryos and embryoid bodies D Piette, M Hendrickx, E Willems, CR Kemp, L Leyns Nature protocols 3 (7), 1194-1201, 2008 | 89 | 2008 |
Wnt inhibition correlates with human embryonic stem cell cardiomyogenesis: a structure–activity relationship study based on inhibitors for the Wnt response M Lanier, D Schade, E Willems, M Tsuda, S Spiering, J Kalisiak, ... Journal of medicinal chemistry 55 (2), 697-708, 2012 | 83 | 2012 |
Patterning of mouse embryonic stem cell-derived pan-mesoderm by Activin A/Nodal and Bmp4 signaling requires Fibroblast Growth Factor activity E Willems, L Leyns Differentiation 76 (7), 745-759, 2008 | 83 | 2008 |
Synthesis and SAR of b-Annulated 1,4-Dihydropyridines Define Cardiomyogenic Compounds as Novel Inhibitors of TGFβ Signaling D Schade, M Lanier, E Willems, K Okolotowicz, P Bushway, C Wahlquist, ... Journal of medicinal chemistry 55 (22), 9946-9957, 2012 | 72 | 2012 |
Natural and synthetic regulators of embryonic stem cell cardiogenesis E Willems, PJ Bushway, M Mercola Pediatric cardiology 30, 635-642, 2009 | 71 | 2009 |
Cyclic stretch of embryonic cardiomyocytes increases proliferation, growth, and expression while repressing Tgf-β signaling I Banerjee, K Carrion, R Serrano, J Dyo, R Sasik, S Lund, E Willems, ... Journal of molecular and cellular cardiology 79, 133-144, 2015 | 64 | 2015 |
Coordinate Nodal and BMP inhibition directs Baf60c-dependent cardiomyocyte commitment W Cai, S Albini, K Wei, E Willems, RM Guzzo, M Tsuda, L Giordani, ... Genes & development 27 (21), 2332-2344, 2013 | 56 | 2013 |
Quantitative transcriptomics using designed primer-based amplification V Bhargava, P Ko, E Willems, M Mercola, S Subramaniam Scientific reports 3 (1), 1740, 2013 | 55 | 2013 |
SYNGAP1 controls the maturation of dendrites, synaptic function, and network activity in developing human neurons N Llamosas, V Arora, R Vij, M Kilinc, L Bijoch, C Rojas, A Reich, ... Journal of Neuroscience 40 (41), 7980-7994, 2020 | 47 | 2020 |
Site-specific Phosphorylation and Caspase Cleavage of GFAP Are New Markers of Alexander Disease Severity NTS Rachel A Battaglia, Adriana S Beltran, Samed Delic, Raluca Dumitru ... eLife 8, e47789, 2019 | 47 | 2019 |