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Yvonne Genzel
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Metabolic effects of influenza virus infection in cultured animal cells: Intra-and extracellular metabolite profiling
JB Ritter, AS Wahl, S Freund, Y Genzel, U Reichl
BMC systems biology 4, 1-22, 2010
2322010
Enhancing the enantioselectivity of an epoxide hydrolase by directed evolution
MT Reetz, C Torre, A Eipper, R Lohmer, M Hermes, B Brunner, ...
Organic letters 6 (2), 177-180, 2004
2012004
Continuous cell lines as a production system for influenza vaccines
Y Genzel, U Reichl
Expert review of vaccines 8 (12), 1681-1692, 2009
1952009
Metabolism of MDCK cells during cell growth and influenza virus production in large-scale microcarrier culture
Y Genzel, I Behrendt, S König, H Sann, U Reichl
Vaccine 22 (17-18), 2202-2208, 2004
1942004
Wave microcarrier cultivation of MDCK cells for influenza virus production in serum containing and serum-free media
Y Genzel, RM Olmer, B Schäfer, U Reichl
Vaccine 24 (35-36), 6074-6087, 2006
1552006
Substitution of glutamine by pyruvate to reduce ammonia formation and growth inhibition of mammalian cells
Y Genzel, JB Ritter, S König, R Alt, U Reichl
Biotechnology progress 21 (1), 58-69, 2005
1412005
Bioreactors for high cell density and continuous multi-stage cultivations: options for process intensification in cell culture-based viral vaccine production
F Tapia, D Vázquez-Ramírez, Y Genzel, U Reichl
Applied microbiology and biotechnology 100, 2121-2132, 2016
1402016
Designing cell lines for viral vaccine production: Where do we stand?
Y Genzel
Biotechnology journal 10 (5), 728-740, 2015
1272015
New avian suspension cell lines provide production of influenza virus and MVA in serum-free media: studies on growth, metabolism and virus propagation
V Lohr, A Rath, Y Genzel, I Jordan, V Sandig, U Reichl
Vaccine 27 (36), 4975-4982, 2009
1252009
Serum-free influenza virus production avoiding washing steps and medium exchange in large-scale microcarrier culture
Y Genzel, M Fischer, U Reichl
Vaccine 24 (16), 3261-3272, 2006
1252006
High cell density cultivations by alternating tangential flow (ATF) perfusion for influenza A virus production using suspension cells
Y Genzel, T Vogel, J Buck, I Behrendt, DV Ramirez, G Schiedner, I Jordan, ...
Vaccine 32 (24), 2770-2781, 2014
1232014
MDCK and Vero cells for influenza virus vaccine production: a one-to-one comparison up to lab-scale bioreactor cultivation
Y Genzel, C Dietzsch, E Rapp, J Schwarzer, U Reichl
Applied microbiology and biotechnology 88, 461-475, 2010
1222010
Simultaneous extraction of several metabolites of energy metabolism and related substances in mammalian cells: optimization using experimental design
JB Ritter, Y Genzel, U Reichl
Analytical biochemistry 373 (2), 349-369, 2008
1212008
Quantitative analysis of cellular proteome alterations in human influenza A virus‐infected mammalian cell lines
D Vester, E Rapp, D Gade, Y Genzel, U Reichl
Proteomics 9 (12), 3316-3327, 2009
1162009
Continuous influenza virus production in cell culture shows a periodic accumulation of defective interfering particles
T Frensing, FS Heldt, A Pflugmacher, I Behrendt, I Jordan, D Flockerzi, ...
PloS one 8 (9), e72288, 2013
1112013
Infection dynamics and virus-induced apoptosis in cell culture-based influenza vaccine production—Flow cytometry and mathematical modeling
J Schulze-Horsel, M Schulze, G Agalaridis, Y Genzel, U Reichl
Vaccine 27 (20), 2712-2722, 2009
1112009
Glycan analysis in cell culture-based influenza vaccine production: influence of host cell line and virus strain on the glycosylation pattern of viral hemagglutinin
J Schwarzer, E Rapp, R Hennig, Y Genzel, I Jordan, V Sandig, U Reichl
Vaccine 27 (32), 4325-4336, 2009
1102009
Bioreactor concepts for cell culture-based viral vaccine production
LE Gallo–Ramírez, A Nikolay, Y Genzel, U Reichl
Expert review of Vaccines 14 (9), 1181-1195, 2015
1092015
Harvesting and concentration of human influenza A virus produced in serum‐free mammalian cell culture for the production of vaccines
B Kalbfuss, Y Genzel, M Wolff, A Zimmermann, R Morenweiser, U Reichl
Biotechnology and bioengineering 97 (1), 73-85, 2007
1092007
A new MDCK suspension line cultivated in a fully defined medium in stirred-tank and wave bioreactor
V Lohr, Y Genzel, I Behrendt, K Scharfenberg, U Reichl
Vaccine 28 (38), 6256-6264, 2010
1072010
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