Valerie L. Dufour
Valerie L. Dufour
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Mutation-independent rhodopsin gene therapy by knockdown and replacement with a single AAV vector
AV Cideciyan, R Sudharsan, VL Dufour, MT Massengill, S Iwabe, ...
Proceedings of the National Academy of Sciences 115 (36), E8547-E8556, 2018
Optimization of retinal gene therapy for X-linked retinitis pigmentosa due to RPGR mutations
WA Beltran, AV Cideciyan, SE Boye, GJ Ye, S Iwabe, VL Dufour, ...
Molecular Therapy 25 (8), 1866-1880, 2017
BEST1 gene therapy corrects a diffuse retina-wide microdetachment modulated by light exposure
SGJGDA Karina E. Guziewicz, Artur V. Cideciyan, William A. Beltran, András M ...
PNAS, 2018
Overlap of abnormal photoreceptor development and progressive degeneration in Leber congenital amaurosis caused by NPHP5 mutation
LM Downs, EM Scott, AV Cideciyan, S Iwabe, V Dufour, KL Gardiner, ...
Human molecular genetics 25 (19), 4211-4226, 2016
Long-term structural outcomes of late-stage RPE65 gene therapy
KL Gardiner, AV Cideciyan, M Swider, VL Dufour, A Sumaroka, ...
Molecular Therapy 28 (1), 266-278, 2020
Effect of topical ophthalmic dorzolamide (2%)–timolol (0.5%) solution and ointment on intraocular pressure in normal horses
KL Tofflemire, EM Whitley, AM Flinn, VL Dufour, G Ben‐Shlomo, ...
Veterinary ophthalmology 18 (6), 457-461, 2015
Underdeveloped RPE apical domain underlies lesion formation in canine bestrophinopathies
KE Guziewicz, E McTish, VL Dufour, K Zorych, A Dhingra, ...
Retinal Degenerative Diseases, 309-315, 2018
Dose Range Finding Studies with Two RPGR Transgenes in a Canine Model of X-linked Retinitis Pigmentosa Treated with Subretinal Gene Therapy
C Song, VLL Dufour, AV Cideciyan, G Ye, M Swider, J Newmark, ...
Human Gene Therapy, 2020
Evaluation of AAV2tYF-GRK1-RPGR vectors in a canine model of RPGR-XLRP
G Ye, WA Beltran, VL Dufour, FP Marinho, I Martynyuk, C Song, D Knop, ...
Investigative Ophthalmology & Visual Science 58 (8), 4486-4486, 2017
Toxicity and Efficacy Evaluation of an AAV Vector Expressing Codon-Optimized RPGR Delivered by Subretinal Injection in a Canine Model of X-linked Retinitis Pigmentosa.
VLL Dufour, AV Cideciyan, GJ Ye, C Song, A Timmers, P Habecker, ...
Hum. gene ther, 2020
Long-term longitudinal assessment of functional rescue in mutant XLRP dogs after RPGR gene augmentation therapy
WA Beltran, VL Dufour, SM Ainsworth, K Roszak, GD Aguirre
Investigative Ophthalmology & Visual Science 60 (9), 4031-4031, 2019
Long-term preservation of photoreceptor function and structure following early-stage treatment by AAV-mediated gene augmentation in canine model of NPHP5 Leber congenital amaurosis
GD Aguirre, AV Cideciyan, SL Boye, S Iwabe, V Dufour, M Swider, ...
Investigative Ophthalmology & Visual Science 59 (9), 6006-6006, 2018
Isolated population helps tease out a third locus underlying a multigenic form of canine RPGRIP1 cone-rod dystrophy
K Miyadera, L Murgiano, C Spector, FP Marinho, V Dufour, RG Das, ...
Investigative Ophthalmology & Visual Science 59 (9), 1438-1438, 2018
ESGCT XXV Anniversary Congress in Collaboration with the German Society for Gene Therapy October 17–20, 2017 Berlin, Germany
SM Maffioletti, S Sarcar, A Henderson, I Mannhardt, L Pinton, LA Moyle, ...
Human Gene Therapy 28 (12), A1-A125, 2017
Directed evolution of AAV vectors guided by deep sequencing creates variants that bypass structural barriers in canine retina
LC Byrne, M Visel, VL Dufour, FP Marinho, GD Aguirre, WA Beltran, ...
MOLECULAR THERAPY 25 (5), 232-233, 2017
AAV-mediated gene augmentation restores retinal function and vision in the canine model of NPHP5 Leber congenital amaurosis
GD Aguirre, AV Cideciyan, SL Boye, S Iwabe, V Dufour, FP Marinho, ...
Investigative Ophthalmology & Visual Science 57 (12), 2016
A newly recognized canine phenotype of early-onset retinal degeneration
KE Guziewicz, V Dufour, L Lew, BT Kendrick, AR Garcia, WA Beltran, ...
Investigative Ophthalmology & Visual Science 61 (7), 2792-2792, 2020
AAV capsid variants target canine and primate bipolar cells after subretinal and intravitreal delivery
WA Beltran, N Dolgova, VL Dufour, I Simone, RF Boyd, JT Bartoe, ...
Investigative Ophthalmology & Visual Science 61 (7), 4489-4489, 2020
Subretinal transplantation and survival of hESC-derived photoreceptor precursor cells in normal canine eyes
AR Garcia, V Dufour, J Phillips, N Dolgova, A Ludwig, S Stuedemann, ...
Investigative Ophthalmology & Visual Science 61 (7), 796-796, 2020
In-vivo longitudinal changes in thickness of the postnatal canine retina
VL Dufour, Y Yu, W Pan, GS Ying, GD Aguirre, WA Beltran
Experimental Eye Research 192, 107926, 2020
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