Aaron N. Brooks
Aaron N. Brooks
Associate Director, Genetic Design @ Ginkgo Bioworks
Verified email at - Homepage
Cited by
Cited by
Adaptation of cells to new environments
AN Brooks, S Turkarslan, KD Beer, F Yin Lo, NS Baliga
Wiley Interdisciplinary Reviews: Systems Biology and Medicine 3 (5), 544-561, 2011
Macromolecular networks and intelligence in microorganisms
HV Westerhoff, AN Brooks, E Simeonidis, R García-Contreras, F He, ...
Frontiers in microbiology 5, 379, 2014
A system‐level model for the microbial regulatory genome
AN Brooks, DJ Reiss, A Allard, WJ Wu, DM Salvanha, CL Plaisier, ...
Molecular systems biology 10 (7), 740, 2014
Data-driven integration of genome-scale regulatory and metabolic network models
S Imam, S Schäuble, AN Brooks, NS Baliga, ND Price
Frontiers in microbiology 6, 409, 2015
Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions
Y Zhao, C Coelho, AL Hughes, L Lazar-Stefanita, S Yang, AN Brooks, ...
Cell 186 (24), 5220-5236. e16, 2023
Design, construction, and functional characterization of a tRNA neochromosome in yeast
D Schindler, RSK Walker, S Jiang, AN Brooks, Y Wang, CA Müller, ...
Cell 186 (24), 5237-5253. e22, 2023
Evolution of context dependent regulation by expansion of feast/famine regulatory proteins
CL Plaisier, FY Lo, J Ashworth, AN Brooks, KD Beer, A Kaur, M Pan, ...
BMC systems biology 8, 1-14, 2014
Transcriptional neighborhoods regulate transcript isoform lengths and expression levels
AN Brooks, AL Hughes, S Clauder-Münster, LA Mitchell, JD Boeke, ...
Science 375 (6584), 1000-1005, 2022
Evolthon: A community endeavor to evolve lab evolution
S Kaminski Strauss, D Schirman, G Jona, AN Brooks, AM Kunjapur, ...
PLoS biology 17 (3), e3000182, 2019
Deep mutational scanning of essential bacterial proteins can guide antibiotic development
L Dewachter, AN Brooks, K Noon, C Cialek, A Clark-ElSayed, T Schalck, ...
nature communications 14 (1), 241, 2023
Disrupting the ArcA regulatory network amplifies the fitness cost of tetracycline resistance in Escherichia coli
ML Arrieta-Ortiz, M Pan, A Kaur, E Pepper-Tunick, V Srinivas, A Dash, ...
Msystems 8 (1), e00904-22, 2023
MtrA modulates Mycobacterium tuberculosis cell division in host microenvironments to mediate intrinsic resistance and drug tolerance
EJR Peterson, AN Brooks, DJ Reiss, A Kaur, J Do, M Pan, WJ Wu, ...
Cell Reports 42 (8), 2023
MtrA regulation of essential peptidoglycan cleavage in Mycobacterium tuberculosis during infection
EJR Peterson, AN Brooks, DJ Reiss, A Kaur, WJ Wu, R Morrison, ...
BioRxiv, 2021.02. 25.432019, 2021
Methods for isolating and/or obtaining captured polynucleotide fragments
J Cosimo, SA JOHANSSON, AN Brooks, A Hughes, LM Steinmetz
US Patent App. 18/501,530, 2024
Automated and Computational Approaches to Metabolic Engineering
G Sriram, A Brooks
SIMB 2023 Annual Meeting, 2023
Genome-wide rationally-designed mutations leading to enhanced cellobiohydrolase i production in s. cerevisiae
E Abbate, K Krouse, A Brooks, T Shepherd, N Krishnamurthy
WO Patent WO2023028521A1, 2023
System and method for gene editing cassette design
A Halweg-Edwards, J Shorenstein, A Garst, C Struble, M Gander, J Kim, ...
US Patent US20220246235A1, 2022
SYGNALing a Red Light for Glioblastoma
AN Brooks, WF Mueller, LM Steinmetz
Cell Systems 3 (2), 118-120, 2016
Data-driven integration of genome-scale regulatory and metabolic network models
AN Brooks, NS Baliga
Data-driven inference of dynamic transcriptional regulatory mechanisms in prokaryotes: a systems perspective
AN Brooks
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