Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin T Schneider-Poetsch, J Ju, DE Eyler, Y Dang, S Bhat, WC Merrick, ... Nature chemical biology 6 (3), 209-217, 2010 | 1158 | 2010 |
XPB, a subunit of TFIIH, is a target of the natural product triptolide DV Titov, B Gilman, QL He, S Bhat, WK Low, Y Dang, M Smeaton, ... Nature chemical biology 7 (3), 182-188, 2011 | 507 | 2011 |
The HBV drug entecavir—effects on HIV-1 replication and resistance MA McMahon, BL Jilek, TP Brennan, L Shen, Y Zhou, M Wind-Rotolo, ... New England Journal of Medicine 356 (25), 2614-2621, 2007 | 385 | 2007 |
Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation S Xing, CK Bullen, NS Shroff, L Shan, HC Yang, JL Manucci, S Bhat, ... Journal of virology 85 (12), 6060-6064, 2011 | 238 | 2011 |
Inhibition of angiogenesis by the antifungal drug itraconazole CR Chong, J Xu, J Lu, S Bhat, DJ Sullivan Jr, JO Liu ACS chemical biology 2 (4), 263-270, 2007 | 238 | 2007 |
Effect of nitroxoline on angiogenesis and growth of human bladder cancer JS Shim, Y Matsui, S Bhat, BA Nacev, J Xu, HC Bhang, S Dhara, KC Han, ... Journal of the National Cancer Institute 102 (24), 1855-1873, 2010 | 129 | 2010 |
Salicylanilide derivatives block Mycobacterium tuberculosis through inhibition of isocitrate lyase and methionine aminopeptidase M Krátký, J Vinšová, E Novotná, J Mandíková, V Wsól, F Trejtnar, ... Tuberculosis, 2012 | 92 | 2012 |
Rapamycin-inspired macrocycles with new target specificity Z Guo, SY Hong, J Wang, S Rehan, W Liu, H Peng, M Das, W Li, S Bhat, ... Nature chemistry 11 (3), 254-263, 2019 | 90 | 2019 |
Optimization of the potency and pharmacokinetic properties of a macrocyclic ghrelin receptor agonist (Part I): development of ulimorelin (TZP-101) from hit to clinic HR Hoveyda, E Marsault, R Gagnon, AP Mathieu, M Vézina, A Landry, ... Journal of medicinal chemistry 54 (24), 8305-8320, 2011 | 87 | 2011 |
Reaction of Azides with Tetrathiomolybdate: reduction and imine formation AR Ramesha, S Bhat, S Chandrasekaran The Journal of Organic Chemistry 60 (23), 7682-7683, 1995 | 80 | 1995 |
Methionine aminopeptidases from Mycobacterium tuberculosis as novel antimycobacterial targets O Olaleye, TR Raghunand, S Bhat, J He, S Tyagi, G Lamichhane, P Gu, ... Chemistry & biology 17 (1), 86-97, 2010 | 79 | 2010 |
Fumagillin and Fumarranol Interact with P. falciparum Methionine Aminopeptidase 2 and Inhibit Malaria Parasite Growth In Vitro and In Vivo X Chen, S Xie, S Bhat, N Kumar, TA Shapiro, JO Liu Chemistry & biology 16 (2), 193-202, 2009 | 68 | 2009 |
Substrate-dependent targeting of eukaryotic translation initiation factor 4A by pateamine A: negation of domain-linker regulation of activity WK Low, Y Dang, S Bhat, D Romo, JO Liu Chemistry & biology 14 (6), 715-727, 2007 | 65 | 2007 |
Inhibition of Amyloid A Amyloidogenesis in vivo and in Tissue Culture by 4-Deoxy Analogues of Peracetylated 2-Acetamido-2-Deoxy-α-and β-d-Glucose: Implications for the … R Kisilevsky, WA Szarek, JB Ancsin, E Elimova, S Marone, S Bhat, ... The American journal of pathology 164 (6), 2127-2137, 2004 | 64 | 2004 |
UDP-Gal: GlcNAc-R β1, 4-galactosyltransferase—a target enzyme for drug design. Acceptor specificity and inhibition of the enzyme I Brockhausen, M Benn, S Bhat, S Marone, JG Riley, P Montoya-Peleaz, ... Glycoconjugate journal 23, 525-541, 2006 | 61 | 2006 |
Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation S Xing, S Bhat, NS Shroff, H Zhang, JA Lopez, JB Margolick, JO Liu, ... Journal of antimicrobial chemotherapy 67 (2), 398-403, 2012 | 55 | 2012 |
Impact of absolute stereochemistry on the antiangiogenic and antifungal activities of itraconazole W Shi, BA Nacev, S Bhat, JO Liu ACS medicinal chemistry letters 1 (4), 155-159, 2010 | 54 | 2010 |
Substituted oxines inhibit endothelial cell proliferation and angiogenesis S Bhat, JS Shim, F Zhang, CR Chong, JO Liu Organic & biomolecular chemistry 10 (15), 2979-2992, 2012 | 53 | 2012 |
Efficient parallel synthesis of macrocyclic peptidomimetics E Marsault, HR Hoveyda, R Gagnon, ML Peterson, M Vézina, ... Bioorganic & medicinal chemistry letters 18 (16), 4731-4735, 2008 | 49 | 2008 |
Characterization of clioquinol and analogues as novel inhibitors of methionine aminopeptidases from Mycobacterium tuberculosis O Olaleye, TR Raghunand, S Bhat, C Chong, P Gu, J Zhou, Y Zhang, ... Tuberculosis 91, S61-S65, 2011 | 48 | 2011 |