The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission M Popoli, Z Yan, BS McEwen, G Sanacora Nature Reviews Neuroscience 13 (1), 22-37, 2012 | 1658 | 2012 |
Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants RS Duman, GK Aghajanian, G Sanacora, JH Krystal Nature medicine 22 (3), 238-249, 2016 | 1567 | 2016 |
Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications S Sen, R Duman, G Sanacora Biological psychiatry 64 (6), 527-532, 2008 | 1533 | 2008 |
Towards a glutamate hypothesis of depression: an emerging frontier of neuropsychopharmacology for mood disorders G Sanacora, G Treccani, M Popoli Neuropharmacology 62 (1), 63-77, 2012 | 1233 | 2012 |
Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders G Sanacora, CA Zarate, JH Krystal, HK Manji Nature reviews Drug discovery 7 (5), 426-437, 2008 | 1103 | 2008 |
Subtype-specific alterations of γ-aminobutyric acid and glutamatein patients with major depression G Sanacora, R Gueorguieva, CN Epperson, YT Wu, M Appel, ... Archives of general psychiatry 61 (7), 705-713, 2004 | 1032 | 2004 |
Altered connectivity in depression: GABA and glutamate neurotransmitter deficits and reversal by novel treatments RS Duman, G Sanacora, JH Krystal Neuron 102 (1), 75-90, 2019 | 835 | 2019 |
Reduced cortical γ-aminobutyric acid levels in depressed patients determined by proton magnetic resonance spectroscopy G Sanacora, GF Mason, DL Rothman, KL Behar, F Hyder, OAC Petroff, ... Archives of general psychiatry 56 (11), 1043-1047, 1999 | 806 | 1999 |
Inhibition of hypothalamic neuropeptide Y gene expression by insulin. MW Schwartz, AJ Sipols, JL Marks, G Sanacora, JD White, A Scheurink, ... Endocrinology 130 (6), 3608-3616, 1992 | 751 | 1992 |
The effect of a single dose of intravenous ketamine on suicidal ideation: a systematic review and individual participant data meta-analysis ST Wilkinson, ED Ballard, MH Bloch, SJ Mathew, JW Murrough, A Feder, ... American journal of psychiatry 175 (2), 150-158, 2018 | 670 | 2018 |
Reduced brain serotonin transporter availability in major depression as measured by [123I]-2β-carbomethoxy-3β-(4-iodophenyl) tropane and single photon emission computed tomography RT Malison, LH Price, R Berman, CH van Dyck, GH Pelton, L Carpenter, ... Biological psychiatry 44 (11), 1090-1098, 1998 | 643 | 1998 |
Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments JH Krystal, G Sanacora, H Blumberg, A Anand, DS Charney, G Marek, ... Molecular psychiatry 7 (1), S71-S80, 2002 | 634 | 2002 |
Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors G Sanacora, GF Mason, DL Rothman, JH Krystal American Journal of Psychiatry 159 (4), 663-665, 2002 | 560 | 2002 |
A double-blind, randomized, placebo-controlled, dose-frequency study of intravenous ketamine in patients with treatment-resistant depression JB Singh, M Fedgchin, EJ Daly, P De Boer, K Cooper, P Lim, C Pinter, ... American Journal of Psychiatry 173 (8), 816-826, 2016 | 550 | 2016 |
Increased cortical GABA concentrations in depressed patients receiving ECT G Sanacora, GF Mason, DL Rothman, F Hyder, JJ Ciarcia, RB Ostroff, ... American Journal of Psychiatry 160 (3), 577-579, 2003 | 550 | 2003 |
Glial pathology in an animal model of depression: reversal of stress-induced cellular, metabolic and behavioral deficits by the glutamate-modulating drug riluzole M Banasr, GMI Chowdhury, R Terwilliger, SS Newton, RS Duman, ... Molecular psychiatry 15 (5), 501-511, 2010 | 537 | 2010 |
Efficacy and safety of intranasal esketamine for the rapid reduction of symptoms of depression and suicidality in patients at imminent risk for suicide: results of a double … CM Canuso, JB Singh, M Fedgchin, L Alphs, R Lane, P Lim, C Pinter, ... American journal of psychiatry 175 (7), 620-630, 2018 | 505 | 2018 |
Rapid-acting glutamatergic antidepressants: the path to ketamine and beyond JH Krystal, G Sanacora, RS Duman Biological psychiatry 73 (12), 1133-1141, 2013 | 499 | 2013 |
A consensus statement on the use of ketamine in the treatment of mood disorders G Sanacora, MA Frye, W McDonald, SJ Mathew, MS Turner, ... JAMA psychiatry 74 (4), 399-405, 2017 | 494 | 2017 |
Synthesizing the evidence for ketamine and esketamine in treatment-resistant depression: an international expert opinion on the available evidence and implementation RS McIntyre, JD Rosenblat, CB Nemeroff, G Sanacora, JW Murrough, ... American Journal of Psychiatry 178 (5), 383-399, 2021 | 485 | 2021 |