| Open source drug discovery with the malaria box compound collection for neglected diseases and beyond WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ... PLoS pathogens 12 (7), e1005763, 2016 | 305 | 2016 |
| Mapping the cellular response to small molecules using chemogenomic fitness signatures AY Lee, RP St. Onge, MJ Proctor, IM Wallace, AH Nile, PA Spagnuolo, ... Science 344 (6180), 208-211, 2014 | 270 | 2014 |
| Quantitative CRISPR interference screens in yeast identify chemical-genetic interactions and new rules for guide RNA design JD Smith, S Suresh, U Schlecht, M Wu, O Wagih, G Peltz, RW Davis, ... Genome biology 17, 1-16, 2016 | 223 | 2016 |
| HEx: A heterologous expression platform for the discovery of fungal natural products CJB Harvey, M Tang, U Schlecht, J Horecka, CR Fischer, HC Lin, J Li, ... Science advances 4 (4), eaar5459, 2018 | 212 | 2018 |
| Expression profiling of mammalian male meiosis and gametogenesis identifies novel candidate genes for roles in the regulation of fertility U Schlecht, P Demougin, R Koch, L Hermida, C Wiederkehr, ... Molecular Biology of the cell 15 (3), 1031-1043, 2004 | 163 | 2004 |
| Gene Annotation and Drug Target Discovery in Candida albicans with a Tagged Transposon Mutant Collection J Oh, E Fung, U Schlecht, RW Davis, G Giaever, RP St. Onge, ... PLoS pathogens 6 (10), e1001140, 2010 | 121 | 2010 |
| Multiplex assay for condition-dependent changes in protein–protein interactions U Schlecht, M Miranda, S Suresh, RW Davis, RP St. Onge Proceedings of the National Academy of Sciences 109 (23), 9213-9218, 2012 | 81 | 2012 |
| Evidence that meningeal mast cells can worsen stroke pathology in mice A Arac, MA Grimbaldeston, ARB Nepomuceno, O Olayiwola, MP Pereira, ... The American journal of pathology 184 (9), 2493-2504, 2014 | 67 | 2014 |
| Mining meiosis and gametogenesis with DNA microarrays U Schlecht, M Primig REPRODUCTION-CAMBRIDGE- 125 (4), 447-456, 2003 | 57 | 2003 |
| A method for high‐throughput production of sequence‐verified DNA libraries and strain collections JD Smith, U Schlecht, W Xu, S Suresh, J Horecka, MJ Proctor, RS Aiyar, ... Molecular systems biology 13 (2), 913, 2017 | 56 | 2017 |
| Biological characterization of gene response in Rpe65‐/‐mouse model of Leber's congenital amaurosis during progression of the disease S Cottet, L Michaut, G Boisset, U Schlecht, W Gehring, DF Schorderet The FASEB journal 20 (12), 2036-2049, 2006 | 54 | 2006 |
| Quantitative analysis of protein interaction network dynamics in yeast A Celaj, U Schlecht, JD Smith, W Xu, S Suresh, M Miranda, AM Aparicio, ... Molecular Systems Biology 13 (7), 934, 2017 | 52 | 2017 |
| A scalable double-barcode sequencing platform for characterization of dynamic protein-protein interactions U Schlecht, Z Liu, JR Blundell, RP St. Onge, SF Levy Nature communications 8 (1), 15586, 2017 | 46 | 2017 |
| Genome-wide expression profiling, in vivo DNA binding analysis, and probabilistic motif prediction reveal novel Abf1 target genes during fermentation, respiration, and … U Schlecht, I Erb, P Demougin, N Robine, V Borde, E Nimwegen, ... Molecular biology of the cell 19 (5), 2193-2207, 2008 | 40 | 2008 |
| Endogenous membrane tumor necrosis factor (TNF) is a potent amplifier of TNF receptor 1-mediated apoptosis M Weingärtner, D Siegmund, U Schlecht, M Fotin-Mleczek, P Scheurich, ... Journal of Biological Chemistry 277 (38), 34853-34859, 2002 | 35 | 2002 |
| Reversible surface thiol immobilization of carboxyl group containing haptens to a biacore biosensor chip enabling repeated usage of a single sensor surface U Schlecht, Y Nomura, T Bachmann, I Karube Bioconjugate Chemistry 13 (2), 188-193, 2002 | 34 | 2002 |
| Recent progress in nucleic acids isotachophoresis V Datinská, I Voráčová, U Schlecht, J Berka, F Foret Journal of Separation Science 41 (1), 236-247, 2018 | 30 | 2018 |
| A functional screen for copper homeostasis genes identifies a pharmacologically tractable cellular system U Schlecht, S Suresh, W Xu, AM Aparicio, A Chu, MJ Proctor, RW Davis, ... BMC genomics 15, 1-14, 2014 | 28 | 2014 |
| Forward chemical genetics in yeast for discovery of chemical probes targeting metabolism R St. Onge, U Schlecht, C Scharfe, M Evangelista Molecules 17 (11), 13098-13115, 2012 | 28 | 2012 |
| Database model and specification of GermOnline Release 2.0, a cross-species community annotation knowledgebase on germ cell differentiation C Wiederkehr, R Basavaraj, CS De Menthičre, R Koch, U Schlecht, ... Bioinformatics 20 (5), 808-811, 2004 | 25 | 2004 |
