Signatures of mutational processes in human cancer LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ... nature 500 (7463), 415-421, 2013 | 10392 | 2013 |
Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1932* | 2020 |
What is next generation sequencing? S Behjati, PS Tarpey Archives of Disease in Childhood-Education and Practice 98 (6), 236-238, 2013 | 1390 | 2013 |
Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma N van Rooij, MM van Buuren, D Philips, A Velds, M Toebes, B Heemskerk, ... Journal of Clinical Oncology 31 (32), e439-e442, 2013 | 974 | 2013 |
SoupX removes ambient RNA contamination from droplet-based single-cell RNA sequencing data MD Young, S Behjati Gigascience 9 (12), giaa151, 2020 | 887 | 2020 |
Prediction of acute myeloid leukaemia risk in healthy individuals S Abelson, G Collord, SWK Ng, O Weissbrod, N Mendelson Cohen, ... Nature 559 (7714), 400-404, 2018 | 849 | 2018 |
Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone S Behjati, PS Tarpey, N Presneau, S Scheipl, N Pillay, P Van Loo, ... Nature genetics 45 (12), 1479-1482, 2013 | 841 | 2013 |
High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma C Linnemann, MM Van Buuren, L Bies, EME Verdegaal, R Schotte, ... Nature medicine 21 (1), 81-85, 2015 | 768 | 2015 |
Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors MD Young, TJ Mitchell, FA Vieira Braga, MGB Tran, BJ Stewart, ... science 361 (6402), 594-599, 2018 | 643 | 2018 |
A cell atlas of human thymic development defines T cell repertoire formation JE Park, RA Botting, C Domínguez Conde, DM Popescu, M Lavaert, ... Science 367 (6480), eaay3224, 2020 | 578 | 2020 |
Decoding human fetal liver haematopoiesis DM Popescu, RA Botting, E Stephenson, K Green, S Webb, L Jardine, ... Nature 574 (7778), 365-371, 2019 | 514 | 2019 |
Intra-tumour diversification in colorectal cancer at the single-cell level SF Roerink, N Sasaki, H Lee-Six, MD Young, LB Alexandrov, S Behjati, ... Nature 556 (7702), 457-462, 2018 | 509 | 2018 |
Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes JMC Tubio, Y Li, YS Ju, I Martincorena, SL Cooke, M Tojo, G Gundem, ... Science 345 (6196), 1251343, 2014 | 458 | 2014 |
Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer J Drost, R Van Boxtel, F Blokzijl, T Mizutani, N Sasaki, V Sasselli, J de Ligt, ... Science 358 (6360), 234-238, 2017 | 448 | 2017 |
Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer YS Ju, LB Alexandrov, M Gerstung, I Martincorena, S Nik-Zainal, ... elife 3, e02935, 2014 | 425 | 2014 |
Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers A Shlien, BB Campbell, R De Borja, LB Alexandrov, D Merico, D Wedge, ... Nature genetics 47 (3), 257-262, 2015 | 396 | 2015 |
Genome sequencing of normal cells reveals developmental lineages and mutational processes S Behjati, M Huch, R Van Boxtel, W Karthaus, DC Wedge, AU Tamuri, ... Nature 513 (7518), 422-425, 2014 | 380 | 2014 |
Spatiotemporal immune zonation of the human kidney BJ Stewart, JR Ferdinand, MD Young, TJ Mitchell, KW Loudon, AM Riding, ... Science 365 (6460), 1461-1466, 2019 | 365 | 2019 |
Developmental cell programs are co-opted in inflammatory skin disease G Reynolds, P Vegh, J Fletcher, EFM Poyner, E Stephenson, I Goh, ... Science 371 (6527), eaba6500, 2021 | 358 | 2021 |
Recurrent PTPRB and PLCG1 mutations in angiosarcoma S Behjati, PS Tarpey, H Sheldon, I Martincorena, P Van Loo, G Gundem, ... Nature genetics 46 (4), 376-379, 2014 | 313 | 2014 |