| A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo SA Yuzwa, MS Macauley, JE Heinonen, X Shan, RJ Dennis, Y He, ... Nature chemical biology 4 (8), 483-490, 2008 | 767 | 2008 |
| Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation SA Yuzwa, X Shan, MS Macauley, T Clark, Y Skorobogatko, K Vosseller, ... Nature chemical biology 8 (4), 393-399, 2012 | 599 | 2012 |
| The emerging link between O-GlcNAc and Alzheimer disease Y Zhu, X Shan, SA Yuzwa, DJ Vocadlo Journal of Biological Chemistry 289 (50), 34472-34481, 2014 | 278 | 2014 |
| O-GlcNAc and neurodegeneration: biochemical mechanisms and potential roles in Alzheimer's disease and beyond SA Yuzwa, DJ Vocadlo Chemical Society Reviews 43 (19), 6839-6858, 2014 | 242 | 2014 |
| Developmental emergence of adult neural stem cells as revealed by single-cell transcriptional profiling SA Yuzwa, MJ Borrett, BT Innes, A Voronova, T Ketela, DR Kaplan, ... Cell reports 21 (13), 3970-3986, 2017 | 193 | 2017 |
| Dedifferentiated Schwann cell precursors secreting paracrine factors are required for regeneration of the mammalian digit tip APW Johnston, SA Yuzwa, MJ Carr, N Mahmud, MA Storer, MP Krause, ... Cell stem cell 19 (4), 433-448, 2016 | 180 | 2016 |
| Mesenchymal precursor cells in adult nerves contribute to mammalian tissue repair and regeneration MJ Carr, JS Toma, APW Johnston, PE Steadman, SA Yuzwa, N Mahmud, ... Cell stem cell 24 (2), 240-256. e9, 2019 | 170 | 2019 |
| Mapping O-GlcNAc modification sites on tau and generation of a site-specific O-GlcNAc tau antibody SA Yuzwa, AK Yadav, Y Skorobogatko, T Clark, K Vosseller, DJ Vocadlo Amino acids 40, 857-868, 2011 | 146 | 2011 |
| O-GlcNAc modification of tau directly inhibits its aggregation without perturbing the conformational properties of tau monomers SA Yuzwa, AH Cheung, M Okon, LP McIntosh, DJ Vocadlo Journal of molecular biology 426 (8), 1736-1752, 2014 | 141 | 2014 |
| Pharmacological inhibition of O-GlcNAcase (OGA) prevents cognitive decline and amyloid plaque formation in bigenic tau/APP mutant mice SA Yuzwa, X Shan, BA Jones, G Zhao, ML Woodward, X Li, Y Zhu, ... Molecular neurodegeneration 9, 1-14, 2014 | 139 | 2014 |
| A translational repression complex in developing mammalian neural stem cells that regulates neuronal specification SK Zahr, G Yang, H Kazan, MJ Borrett, SA Yuzwa, A Voronova, ... Neuron 97 (3), 520-537. e6, 2018 | 138 | 2018 |
| Insights into O-linked N-acetylglucosamine ([0-9] O-GlcNAc) processing and dynamics through kinetic analysis of O-GlcNAc transferase and O-GlcNAcase activity on protein substrates DL Shen, TM Gloster, SA Yuzwa, DJ Vocadlo Journal of Biological Chemistry 287 (19), 15395-15408, 2012 | 122 | 2012 |
| Elevation of Global O-GlcNAc in rodents using a selective O-GlcNAcase inhibitor does not cause insulin resistance or perturb glucohomeostasis MS Macauley, X Shan, SA Yuzwa, TM Gloster, DJ Vocadlo Chemistry & biology 17 (9), 949-958, 2010 | 86 | 2010 |
| Post-translational O-GlcNAcylation is essential for nuclear pore integrity and maintenance of the pore selectivity filter Y Zhu, TW Liu, Z Madden, SA Yuzwa, K Murray, S Cecioni, N Zachara, ... Journal of molecular cell biology 8 (1), 2-16, 2016 | 78 | 2016 |
| Acquisition of a unique mesenchymal precursor-like blastema state underlies successful adult mammalian digit tip regeneration MA Storer, N Mahmud, K Karamboulas, MJ Borrett, SA Yuzwa, A Gont, ... Developmental cell 52 (4), 509-524. e9, 2020 | 77 | 2020 |
| Migrating interneurons secrete fractalkine to promote oligodendrocyte formation in the developing mammalian brain A Voronova, SA Yuzwa, BS Wang, S Zahr, C Syal, J Wang, DR Kaplan, ... Neuron 94 (3), 500-516. e9, 2017 | 76 | 2017 |
| Molecular basis for inhibition of GH84 glycoside hydrolases by substituted azepanes: conformational flexibility enables probing of substrate distortion F Marcelo, Y He, SA Yuzwa, L Nieto, J Jiménez-Barbero, M Sollogoub, ... Journal of the American Chemical Society 131 (15), 5390-5392, 2009 | 74 | 2009 |
| Proneurogenic ligands defined by modeling developing cortex growth factor communication networks SA Yuzwa, G Yang, MJ Borrett, G Clarke, GI Cancino, SK Zahr, ... Neuron 91 (5), 988-1004, 2016 | 49 | 2016 |
| Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer MS Butler, M Roshan-Moniri, M Hsing, D Lau, A Kim, P Yen, M Mroczek, ... Oncotarget 8 (26), 42438, 2017 | 46 | 2017 |
| Peripheral nerve single-cell analysis identifies mesenchymal ligands that promote axonal growth JS Toma, K Karamboulas, MJ Carr, A Kolaj, SA Yuzwa, N Mahmud, ... Eneuro 7 (3), 2020 | 43 | 2020 |
