Prevention of experimental autoimmune encephalomyelitis by antibodies against α4βl integrin TA Yednock, C Cannon, LC Fritz, F Sanchez-Madrid, L Steinman, N Karin Nature 356 (6364), 63-66, 1992 | 2271 | 1992 |
The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters PA Wender, DJ Mitchell, K Pattabiraman, ET Pelkey, L Steinman, ... Proceedings of the National Academy of Sciences 97 (24), 13003-13008, 2000 | 2142 | 2000 |
Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis C Lock, G Hermans, R Pedotti, A Brendolan, E Schadt, H Garren, ... Nature medicine 8 (5), 500-508, 2002 | 2096 | 2002 |
Treatment of brain inflammatory diseases by delivering exosome encapsulated anti-inflammatory drugs from the nasal region to the brain X Zhuang, X Xiang, W Grizzle, D Sun, S Zhang, RC Axtell, S Ju, J Mu, ... Molecular Therapy 19 (10), 1769-1779, 2011 | 1444 | 2011 |
Polyarginine enters cells more efficiently than other polycationic homopolymers DJ Mitchell, L Steinman, DT Kim, CG Fathman, JB Rothbard The Journal of Peptide Research 56 (5), 318-325, 2000 | 1383 | 2000 |
The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease S Youssef, O Stüve, JC Patarroyo, PJ Ruiz, JL Radosevich, EM Hur, ... Nature 420 (6911), 78-84, 2002 | 1377 | 2002 |
A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell–mediated tissue damage L Steinman Nature medicine 13 (2), 139-145, 2007 | 1339 | 2007 |
The T lymphocyte in experimental allergic encephalomyelitis SS Zamvil, L Steinman Annual review of immunology 8 (1), 579-621, 1990 | 1331 | 1990 |
Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE). IA Ferber, S Brocke, C Taylor-Edwards, W Ridgway, C Dinisco, ... Journal of immunology (Baltimore, Md.: 1950) 156 (1), 5-7, 1996 | 1268 | 1996 |
Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system L Steinman Cell 85 (3), 299-302, 1996 | 1204 | 1996 |
Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention H Acha-Orbea, DJ Mitchell, L Timmermann, DC Wraith, GS Tausch, ... Cell 54 (2), 263-273, 1988 | 1200 | 1988 |
The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease D Chabas, SE Baranzini, D Mitchell, CCA Bernard, SR Rittling, ... Science 294 (5547), 1731-1735, 2001 | 1091 | 2001 |
Autoantigen microarrays for multiplex characterization of autoantibody responses WH Robinson, C DiGennaro, W Hueber, BB Haab, M Kamachi, EJ Dean, ... Nature medicine 8 (3), 295-301, 2002 | 930 | 2002 |
A molecular basis for MHC class II—associated autoimmunity JA Todd, H Acha-Orbea, JI Bell, N Chao, Z Fronek, CO Jacob, ... Science 240 (4855), 1003-1009, 1988 | 887 | 1988 |
Multiple sclerosis: a two-stage disease L Steinman Nature immunology 2 (9), 762-764, 2001 | 867 | 2001 |
Statin therapy and autoimmune disease: from protein prenylation to immunomodulation J Greenwood, L Steinman, SS Zamvil Nature reviews immunology 6 (5), 358-370, 2006 | 823 | 2006 |
Elaborate interactions between the immune and nervous systems L Steinman Nature immunology 5 (6), 575-581, 2004 | 727 | 2004 |
T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination S Zamvil, P Nelson, J Trotter, D Mitchell, R Knobler, R Fritz, L Steinman Nature 317 (6035), 355-358, 1985 | 697 | 1985 |
T helper type 1 and 17 cells determine efficacy of interferon-β in multiple sclerosis and experimental encephalomyelitis RC Axtell, BA De Jong, K Boniface, LF Van Der Voort, R Bhat, P De Sarno, ... Nature medicine 16 (4), 406-412, 2010 | 664 | 2010 |
How to successfully apply animal studies in experimental allergic encephalomyelitis to research on multiple sclerosis L Steinman, SS Zamvil Annals of neurology 60 (1), 12-21, 2006 | 649 | 2006 |