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Javier Estrada Díez
Javier Estrada Díez
Associate Director, Bristol Myer Squibb
Verified email at bms.com
Title
Cited by
Cited by
Year
Information integration and energy expenditure in gene regulation
J Estrada, F Wong, A DePace, J Gunawardena
Cell 166 (1), 234-244, 2016
1592016
Krüppel expression levels are maintained through compensatory evolution of shadow enhancers
Z Wunderlich, MDJ Bragdon, BJ Vincent, JA White, J Estrada, AH DePace
Cell reports 12 (11), 1740-1747, 2015
692015
Dissecting the sharp response of a canonical developmental enhancer reveals multiple sources of cooperativity
J Park, J Estrada, G Johnson, BJ Vincent, C Ricci-Tam, MDJ Bragdon, ...
Elife 8, e41266, 2019
662019
SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms
Y Wang, M Mohseni, A Grauel, JE Diez, W Guan, S Liang, JE Choi, M Pu, ...
Scientific reports 11 (1), 1399, 2021
572021
Shadow enhancers enable Hunchback bifunctionality in the Drosophila embryo
MV Staller, BJ Vincent, MDJ Bragdon, T Lydiard-Martin, Z Wunderlich, ...
Proceedings of the National Academy of Sciences 112 (3), 785-790, 2015
572015
The appeasement of Doug: a synthetic approach to enhancer biology
BJ Vincent, J Estrada, AH DePace
Integrative Biology 8 (4), 475-484, 2016
552016
Yearly planning meetings: individualized development plans Aren’t just more paperwork
BJ Vincent, C Scholes, MV Staller, Z Wunderlich, J Estrada, J Park, ...
Molecular cell 58 (5), 718-721, 2015
362015
Hunchback is counter-repressed to regulate even-skipped stripe 2 expression in Drosophila embryos
BJ Vincent, MV Staller, F Lopez-Rivera, MDJ Bragdon, ECG Pym, ...
PLoS genetics 14 (9), e1007644, 2018
342018
A gene expression atlas of a bicoid-depleted Drosophila embryo reveals early canalization of cell fate
MV Staller, CC Fowlkes, MDJ Bragdon, Z Wunderlich, J Estrada, ...
Development 142 (3), 587-596, 2015
282015
SiteOut: an online tool to design binding site-free DNA sequences
J Estrada, T Ruiz-Herrero, C Scholes, Z Wunderlich, AH DePace
PLoS One 11 (3), e0151740, 2016
242016
A tunable coarse-grained model for ligand-receptor interaction
T Ruiz-Herrero, J Estrada, R Guantes, DG Miguez
PLoS computational biology 9 (11), e1003274, 2013
222013
Trade-offs and noise tolerance in signal detection by genetic circuits
R Guantes, J Estrada, JF Poyatos
PLoS One 5 (8), e12314, 2010
202010
A Mutation in the Drosophila melanogaster eve Stripe 2 Minimal Enhancer Is Buffered by Flanking Sequences
F López-Rivera, OK Foster Rhoades, BJ Vincent, ECG Pym, ...
G3: Genes, Genomes, Genetics 10 (12), 4473-4482, 2020
162020
Quantitative measurement and thermodynamic modeling of fused enhancers support a two-tiered mechanism for interpreting regulatory DNA
MAH Samee, T Lydiard-Martin, KM Biette, BJ Vincent, MD Bragdon, ...
Cell reports 21 (1), 236-245, 2017
152017
Cellular interrogation: exploiting cell-to-cell variability to discriminate regulatory mechanisms in oscillatory signalling
J Estrada, N Andrew, D Gibson, F Chang, F Gnad, J Gunawardena
PLoS computational biology 12 (7), e1004995, 2016
102016
Proteus: a web-based, context-specific modelling tool for molecular networks
F Gnad, J Estrada, J Gunawardena
Bioinformatics 28 (9), 1284-1286, 2012
52012
Dynamic and structural constraints in signal propagation by regulatory networks
J Estrada, R Guantes
Molecular BioSystems 9 (2), 268-284, 2013
42013
Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance
JL Cotton, J Estrada Diez, V Sagar, J Chen, M Piquet, J Alford, Y Song, ...
Cancer Research 83 (21), 3611-3623, 2023
22023
BINDING SITE-DEPLETED DNA FOR QUANTITATIVE STUDIES OF ENHANCER AND TF FUNCTION
J Estrada, T Ruiz-Herrero, C Scholes, Z Wunderlich, AH DePace
Integrating Regulatory Information in Eukaryotic Transcription, 69, 2020
2020
Caudal counter-represses Hunchback to regulate even-skipped stripe 2 expression in Drosophila embryos
BJ Vincent, MV Staller, F Lopez-Rivera, MDJ Bragdon, Z Wunderlich, ...
bioRxiv, 226373, 2017
2017
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