B-cell receptor signaling in chronic lymphocytic leukemia FK Stevenson, S Krysov, AJ Davies, AJ Steele, G Packham Blood, The Journal of the American Society of Hematology 118 (16), 4313-4320, 2011 | 494 | 2011 |
The outcome of B-cell receptor signaling in chronic lymphocytic leukemia: proliferation or anergy G Packham, S Krysov, A Allen, N Savelyeva, AJ Steele, F Forconi, ... haematologica 99 (7), 1138, 2014 | 145 | 2014 |
Detection of serum reverse transcriptase activity in patients with ALS and unaffected blood relatives AJ Steele, A Al-Chalabi, K Ferrante, ME Cudkowicz, RH Brown Jr, ... Neurology 64 (3), 454-458, 2005 | 132 | 2005 |
Autophagy inhibition-mediated epithelial–mesenchymal transition augments local myofibroblast differentiation in pulmonary fibrosis C Hill, J Li, D Liu, F Conforti, CJ Brereton, L Yao, Y Zhou, A Alzetani, ... Cell death & disease 10 (8), 591, 2019 | 129 | 2019 |
IL-4 enhances expression and function of surface IgM in CLL cells MM Aguilar-Hernandez, MD Blunt, R Dobson, A Yeomans, ... Blood, The Journal of the American Society of Hematology 127 (24), 3015-3025, 2016 | 118 | 2016 |
ATM mutation rather than BIRC3 deletion and/or mutation predicts reduced survival in 11q-deleted chronic lymphocytic leukemia: data from the UK LRF CLL4 trial MJJ Rose-Zerilli, J Forster, H Parker, A Parker, AE Rodríguez, T Chaplin, ... haematologica 99 (4), 736, 2014 | 114 | 2014 |
Fixed-duration ibrutinib-venetoclax in patients with chronic lymphocytic leukemia and comorbidities AP Kater, C Owen, C Moreno, G Follows, T Munir, MD Levin, O Benjamini, ... NEJM evidence 1 (7), EVIDoa2200006, 2022 | 113 | 2022 |
The SF3B1 inhibitor spliceostatin A (SSA) elicits apoptosis in chronic lymphocytic leukaemia cells through downregulation of Mcl-1 M Larrayoz, SJ Blakemore, RC Dobson, MD Blunt, MJJ Rose-Zerilli, ... Leukemia 30 (2), 351-360, 2016 | 104 | 2016 |
The sesquiterpene lactone parthenolide induces selective apoptosis of B-chronic lymphocytic leukemia cells in vitro AJ Steele, DT Jones, K Ganeshaguru, VM Duke, BC Yogashangary, ... Leukemia 20 (6), 1073-1079, 2006 | 97 | 2006 |
p53-mediated apoptosis of CLL cells: evidence for a transcription-independent mechanism AJ Steele, AG Prentice, AV Hoffbrand, BC Yogashangary, SM Hart, ... Blood, The Journal of the American Society of Hematology 112 (9), 3827-3834, 2008 | 89 | 2008 |
The JAK3-selective inhibitor PF-956980 reverses the resistance to cytotoxic agents induced by interleukin-4 treatment of chronic lymphocytic leukemia cells: potential for … AJ Steele, AG Prentice, K Cwynarski, AV Hoffbrand, SM Hart, MW Lowdell, ... Blood, The Journal of the American Society of Hematology 116 (22), 4569-4577, 2010 | 86 | 2010 |
Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia H Parker, MJJ Rose-Zerilli, M Larrayoz, R Clifford, J Edelmann, ... Leukemia 30 (11), 2179-2186, 2016 | 80 | 2016 |
Identification in CLL of circulating intraclonal subgroups with varying B-cell receptor expression and function V Coelho, S Krysov, A Steele, M Sanchez Hidalgo, PW Johnson, ... Blood, The Journal of the American Society of Hematology 122 (15), 2664-2672, 2013 | 75 | 2013 |
Selective apoptotic killing of malignant hemopoietic cells by antibody-targeted delivery of an amphipathic peptide AJ Marks, MS Cooper, RJ Anderson, KH Orchard, G Hale, JM North, ... Cancer research 65 (6), 2373-2377, 2005 | 75 | 2005 |
STING activation reverses lymphoma-mediated resistance to antibody immunotherapy LN Dahal, L Dou, K Hussain, R Liu, A Earley, KL Cox, S Murinello, I Tracy, ... Cancer research 77 (13), 3619-3631, 2017 | 74 | 2017 |
p53 and Notch signaling in chronic lymphocytic leukemia: clues to identifying novel therapeutic strategies RG Wickremasinghe, AG Prentice, AJ Steele Leukemia 25 (9), 1400-1407, 2011 | 72 | 2011 |
Surface IgM expression and function are associated with clinical behavior, genetic abnormalities, and DNA methylation in CLL A D’Avola, S Drennan, I Tracy, I Henderson, L Chiecchio, M Larrayoz, ... Blood, The Journal of the American Society of Hematology 128 (6), 816-826, 2016 | 68 | 2016 |
The dual Syk/JAK inhibitor cerdulatinib antagonizes B-cell receptor and microenvironmental signaling in chronic lymphocytic leukemia MD Blunt, S Koehrer, RC Dobson, M Larrayoz, S Wilmore, A Hayman, ... Clinical Cancer Research 23 (9), 2313-2324, 2017 | 66 | 2017 |
Engagement of the B-cell receptor of chronic lymphocytic leukemia cells drives global and MYC-specific mRNA translation A Yeomans, SM Thirdborough, B Valle-Argos, A Linley, S Krysov, ... Blood, The Journal of the American Society of Hematology 127 (4), 449-457, 2016 | 64 | 2016 |
Proteomics profiling of CLL versus healthy B-cells identifies putative therapeutic targets and a subtype-independent signature of spliceosome dysregulation HE Johnston, MJ Carter, M Larrayoz, J Clarke, SD Garbis, D Oscier, ... Molecular & Cellular Proteomics 17 (4), 776-791, 2018 | 60 | 2018 |