Endoplasmic reticulum stress alters ryanodine receptor function in the murine pancreatic β cell WR Yamamoto, RN Bone, P Sohn, F Syed, CA Reissaus, AL Mosley, ... Journal of Biological Chemistry 294 (1), 168-181, 2019 | 101 | 2019 |
MicroRNA 21 targets BCL2 mRNA to increase apoptosis in rat and human beta cells EK Sims, AJ Lakhter, E Anderson-Baucum, T Kono, X Tong, ... Diabetologia 60 (6), 1057-1065, 2017 | 91 | 2017 |
SERCA2 Deficiency Impairs Pancreatic β Cell Function in Response to Diet-Induced Obesity GESCEM Xin Tong, Tatsuyoshi Kono, Emily K. Anderson-Baucum, Wataru Yamamoto diabetes, 2016 | 83 | 2016 |
Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks R Haliyur, X Tong, M Sanyoura, S Shrestha, J Lindner, DC Saunders, ... The Journal of clinical investigation 129 (1), 246-251, 2019 | 82 | 2019 |
Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic β cells XC Xiwen Xiong, Gaihong Wang, Rongya Tao, Pengfei Wu, Tatsuyoshi Kono, Kevin ... Diabetologia, 2015 | 75* | 2015 |
Impaired store-operated calcium entry and STIM1 loss lead to reduced insulin secretion and increased endoplasmic reticulum stress in the diabetic β-cell T Kono, X Tong, S Taleb, RN Bone, H Iida, CC Lee, P Sohn, P Gilon, ... Diabetes 67 (11), 2293-2304, 2018 | 61 | 2018 |
Pancreatic and Duodenal Homeobox Protein 1 (Pdx-1) Modulates Endoplasmic Reticulum Calcium Levels Through Transcriptional Regulation of Sarco-endoplasmic Reticulum Calcium … CEM Justin S. Johnson, Tatsuyoshi Kono, Xin Tong, Wataru Yamamoto, Matthew J ... journal of biological chemistry, 2014 | 52 | 2014 |
Lipid droplet accumulation in human pancreatic islets is dependent on both donor age and health X Tong, C Dai, JT Walker, GG Nair, A Kennedy, RM Carr, M Hebrok, ... Diabetes 69 (3), 342-354, 2020 | 46 | 2020 |
Nitric oxide stress and activation of AMP-activated protein kinase impair β-cell sarcoendoplasmic reticulum calcium ATPase 2b activity and protein stability X Tong, T Kono, C Evans-Molina Cell death & disease 6 (6), e1790-e1790, 2015 | 33 | 2015 |
Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males EM Walker, J Cha, X Tong, M Guo, JH Liu, S Yu, D Iacovazzo, ... Cell reports 37 (2), 2021 | 31 | 2021 |
Cigarette smoke exposure impairs β-cell function through activation of oxidative stress and ceramide accumulation X Tong, Z Chaudhry, CC Lee, RN Bone, S Kanojia, J Maddatu, P Sohn, ... Molecular Metabolism 37, 100975, 2020 | 26 | 2020 |
Phylogenetic study of Oryzoideae species and related taxa of the Poaceae based on atpB-rbcL and ndhF DNA sequences ZL Xu Zeng, Zhengrong Yuan, Xin Tong, Qiushi Li, Weiwei Gao, Minjian Qin Molecular Biology Reports, 2011 | 18* | 2011 |
Lipid droplets’ role in the regulation of β-Cell function and β-Cell demise in type 2 diabetes X Tong, S Liu, R Stein, Y Imai Endocrinology 163 (3), bqac007, 2022 | 15 | 2022 |
Lipid droplets protect human β-cells from lipotoxicity-induced stress and cell identity changes X Tong, R Stein Diabetes 70 (11), 2595-2607, 2021 | 15 | 2021 |
Macrophages and neutrophils are necessary for ER stress-induced β cell loss B Yang, L Yang, Y Wang, LA Maddison, Z Tang, S Haigh, Y Gong, ... Cell reports 40 (8), 2022 | 9 | 2022 |
β Cell Derived MicroRNA 21 Increases Apoptosis and Could Serve as a Biomarker of Type 1 Diabetes Mellitus CEM Emily Sims, Ivan Restrepo, Xin Tong, Tatsuyoshi Kono, Raghavendra Mirmira ADA, 2015 | | 2015 |
Human adipose derived stromal/stem cells (hASCs) protect against STZ-induced hyperglycemia; analysis of hASC-derived paracrine effectors CEM Tatsuyoshi Kono, Emily K. Sims, Dan R. Moss, Wataru Yamamoto, Geonyoung ... stem cells, 2014 | | 2014 |