Jeff Liu
Jeff Liu
University Health Network
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Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations
SA MacParland, JC Liu, XZ Ma, BT Innes, AM Bartczak, BK Gage, ...
Nature communications 9 (1), 4383, 2018
Identification of tumorsphere-and tumor-initiating cells in HER2/Neu-induced mammary tumors
JC Liu, T Deng, RS Lehal, J Kim, E Zacksenhaus
Cancer research 67 (18), 8671-8681, 2007
Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status
Z Jiang, T Deng, R Jones, H Li, JI Herschkowitz, JC Liu, VJ Weigman, ...
The Journal of clinical investigation 120 (9), 3296-3309, 2010
A clinically applicable integrative molecular classification of meningiomas
F Nassiri, J Liu, V Patil, Y Mamatjan, JZ Wang, R Hugh-White, AM Macklin, ...
Nature 597 (7874), 119-125, 2021
Cooperation between Pik3ca and p53 Mutations in Mouse Mammary Tumor FormationMutations in Pik3ca and p53 Cooperate in Breast Cancer Model
JR Adams, K Xu, JC Liu, NMR Agamez, AJ Loch, RG Wong, W Wang, ...
Cancer research 71 (7), 2706-2717, 2011
RB1 and p53 at the crossroad of EMT and triple-negative breast cancer
Z Jiang, R Jones, JC Liu, T Deng, T Robinson, PED Chung, S Wang, ...
Cell cycle 10 (10), 1563-1570, 2011
RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation
RA Jones, TJ Robinson, JC Liu, M Shrestha, V Voisin, YJ Ju, PED Chung, ...
The Journal of clinical investigation 126 (10), 3739-3757, 2016
Combined deletion of P ten and p53 in mammary epithelium accelerates triple‐negative breast cancer with dependency on e EF 2 K
JC Liu, V Voisin, S Wang, DY Wang, RA Jones, A Datti, D Uehling, ...
EMBO molecular medicine 6 (12), 1542-1560, 2014
Combined deletion of P ten and p53 in mammary epithelium accelerates triple‐negative breast cancer with dependency on e EF 2 K
JC Liu, V Voisin, S Wang, DY Wang, RA Jones, A Datti, D Uehling, ...
EMBO molecular medicine 6 (12), 1542-1560, 2014
Mitochondrial OXPHOS induced by RB1 deficiency in breast cancer: implications for anabolic metabolism, stemness, and metastasis
E Zacksenhaus, M Shrestha, JC Liu, I Vorobieva, PED Chung, YJ Ju, ...
Trends in cancer 3 (11), 768-779, 2017
Seventeen-gene signature from enriched Her2/Neu mammary tumor-initiating cells predicts clinical outcome for human HER2+: ERα− breast cancer
JC Liu, V Voisin, GD Bader, T Deng, L Pusztai, WF Symmans, FJ Esteva, ...
Proceedings of the National Academy of Sciences 109 (15), 5832-5837, 2012
High-throughput screen identifies disulfiram as a potential therapeutic for triple-negative breast cancer cells: interaction with IQ motif-containing factors
T Robinson, M Pai, J Liu, F Vizeacoumar, T Sun, S Egan, A Datti, J Huang, ...
Cell Cycle 12 (18), 3013-3024, 2013
RB1 status in triple negative breast cancer cells dictates response to radiation treatment and selective therapeutic drugs
TJW Robinson, JC Liu, F Vizeacoumar, T Sun, N Maclean, SE Egan, ...
PloS one 8 (11), e78641, 2013
Activation of Go-coupled dopamine D2 receptors inhibits ERK1/ERK2 in pituitary cells: a key step in the transcriptional suppression of the prolactin gene
JC Liu, RE Baker, C Sun, VC Sundmark, HP Elsholtz
Journal of Biological Chemistry 277 (39), 35819-35825, 2002
Elevated PI3K signaling drives multiple breast cancer subtypes
JR Adams, NF Schachter, JC Liu, E Zacksenhaus, SE Egan
Oncotarget 2 (6), 435, 2011
Ras signaling is a key determinant for metastatic dissemination and poor survival of luminal breast cancer patients
KL Wright, JR Adams, JC Liu, AJ Loch, RG Wong, CEB Jo, LA Beck, ...
Cancer research 75 (22), 4960-4972, 2015
Identification of CDC25 as a common therapeutic target for triple-negative breast cancer
JC Liu, L Granieri, M Shrestha, DY Wang, I Vorobieva, EA Rubie, R Jones, ...
Cell reports 23 (1), 112-126, 2018
Ketoconazole and Posaconazole Selectively Target HK2-expressing Glioblastoma CellsAzoles Inhibit HK2 and GBM Growth
S Agnihotri, S Mansouri, K Burrell, M Li, Y Mamatjan, J Liu, R Nejad, ...
Clinical Cancer Research 25 (2), 844-855, 2019
Benchmarking to the gold standard: hyaluronan‐oxime hydrogels recapitulate xenograft models with in vitro breast cancer spheroid culture
AEG Baker, LC Bahlmann, RY Tam, JC Liu, AN Ganesh, N Mitrousis, ...
Advanced Materials 31 (36), 1901166, 2019
shRNA Kinome Screen Identifies TBK1 as a Therapeutic Target for HER2+ Breast CancerTBK1/IKKϵ as Targets for HER2+ Breast Cancer
T Deng, JC Liu, PED Chung, D Uehling, A Aman, B Joseph, T Ketela, ...
Cancer research 74 (7), 2119-2130, 2014
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