|Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia|
V Fulci, S Chiaretti, M Goldoni, G Azzalin, N Carucci, S Tavolaro, ...
Blood, The Journal of the American Society of Hematology 109 (11), 4944-4951, 2007
|The estrogen receptor-α-induced microRNA signature regulates itself and its transcriptional response|
L Castellano, G Giamas, J Jacob, RC Coombes, W Lucchesi, ...
Proceedings of the National Academy of Sciences 106 (37), 15732-15737, 2009
|5′ isomiR variation is of functional and evolutionary importance|
GC Tan, E Chan, A Molnar, R Sarkar, D Alexieva, IM Isa, S Robinson, ...
Nucleic acids research 42 (14), 9424-9435, 2014
|MicroRNAs cooperatively inhibit a network of tumor suppressor genes to promote pancreatic tumor growth and progression|
AE Frampton, L Castellano, T Colombo, E Giovannetti, J Krell, J Jacob, ...
Gastroenterology 146 (1), 268-277. e18, 2014
|MicroRNAs targeting oncogenes are down-regulated in pancreatic malignant transformation from benign tumors|
LR Jiao, AE Frampton, J Jacob, L Pellegrino, J Krell, G Giamas, N Tsim, ...
PloS one 7 (2), e32068, 2012
|Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer|
G Giamas, A Filipović, J Jacob, W Messier, H Zhang, D Yang, W Zhang, ...
Nature medicine 17 (6), 715-719, 2011
|Deep sequencing of small RNAs identifies canonical and non-canonical miRNA and endogenous siRNAs in mammalian somatic tissues|
L Castellano, J Stebbing
Nucleic acids research 41 (5), 3339-3351, 2013
|miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts|
L Pellegrino, J Stebbing, VM Braga, AE Frampton, J Jacob, L Buluwela, ...
Nucleic acids research 41 (10), 5400-5412, 2013
|microRNAs with prognostic significance in pancreatic ductal adenocarcinoma: A meta-analysis|
AE Frampton, J Krell, NB Jamieson, TMH Gall, E Giovannetti, N Funel, ...
European journal of cancer 51 (11), 1389-1404, 2015
|Myocardial MiR-30 downregulation triggered by doxorubicin drives alterations in β-adrenergic signaling and enhances apoptosis|
L Roca-Alonso, L Castellano, A Mills, AF Dabrowska, MB Sikkel, ...
Cell death & disease 6 (5), e1754-e1754, 2015
|Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer|
A Harrod, J Fulton, VTM Nguyen, M Periyasamy, L Ramos-Garcia, CF Lai, ...
Oncogene 36 (16), 2286-2296, 2017
|Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion|
VTM Nguyen, I Barozzi, M Faronato, Y Lombardo, JH Steel, N Patel, ...
Nature communications 6, 10044, 2015
|Emerging roles of competing endogenous RNAs in cancer: insights from the regulation of PTEN|
A de Giorgio, J Krell, V Harding, J Stebbing, L Castellano
Molecular and cellular biology 33 (20), 3976-3982, 2013
|Growth arrest-specific transcript 5 associated snoRNA levels are related to p53 expression and DNA damage in colorectal cancer|
J Krell, AE Frampton, R Mirnezami, V Harding, A De Giorgio, LR Alonso, ...
PloS one 9 (6), e98561, 2014
|Mammosphere formation assay from human breast cancer tissues and cell lines|
Y Lombardo, A de Giorgio, CR Coombes, J Stebbing, L Castellano
JoVE (Journal of Visualized Experiments), e52671, 2015
|Downregulation of microRNA-515-5p by the estrogen receptor modulates sphingosine kinase 1 and breast cancer cell proliferation|
FG Pinho, AE Frampton, J Nunes, J Krell, H Alshaker, J Jacob, ...
Cancer research 73 (19), 5936-5948, 2013
|miR‐515‐5p controls cancer cell migration through MARK 4 regulation|
OE Pardo, L Castellano, CE Munro, Y Hu, F Mauri, J Krell, R Lara, ...
EMBO reports 17 (4), 570-584, 2016
|Quantification of pancreatic cancer proteome and phosphorylome: indicates molecular events likely contributing to cancer and activity of drug targets|
D Britton, Y Zen, A Quaglia, S Selzer, V Mitra, C Lößner, S Jung, G Böhm, ...
PLoS One 9 (3), e90948, 2014
|The germline of the malaria mosquito produces abundant miRNAs, endo-siRNAs, piRNAs and 29-nt small RNAs|
L Castellano, E Rizzi, J Krell, M Di Cristina, R Galizi, A Mori, J Tam, ...
BMC genomics 16 (1), 1-16, 2015
|CK1δ modulates the transcriptional activity of ERα via AIB1 in an estrogen-dependent manner and regulates ERα–AIB1 interactions|
G Giamas, L Castellano, Q Feng, U Knippschild, J Jacob, RS Thomas, ...
Nucleic acids research 37 (9), 3110-3123, 2009