| The genetic landscape of a cell M Costanzo, A Baryshnikova, J Bellay, Y Kim, ED Spear, CS Sevier, ... science 327 (5964), 425-431, 2010 | 2520 | 2010 |
| The chemical genomic portrait of yeast: uncovering a phenotype for all genes ME Hillenmeyer, E Fung, J Wildenhain, SE Pierce, S Hoon, W Lee, ... Science 320 (5874), 362-365, 2008 | 1152 | 2008 |
| Defining genetic interaction R Mani, RP St. Onge, JL Hartman IV, G Giaever, FP Roth Proceedings of the National Academy of Sciences 105 (9), 3461-3466, 2008 | 560 | 2008 |
| Systematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletions RPS Onge, R Mani, J Oh, M Proctor, E Fung, RW Davis, C Nislow, ... Nature genetics 39 (2), 199-206, 2007 | 372 | 2007 |
| Open source drug discovery with the malaria box compound collection for neglected diseases and beyond WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ... PLoS pathogens 12 (7), e1005763, 2016 | 305 | 2016 |
| Mapping the cellular response to small molecules using chemogenomic fitness signatures AY Lee, RP St. Onge, MJ Proctor, IM Wallace, AH Nile, PA Spagnuolo, ... Science 344 (6180), 208-211, 2014 | 270 | 2014 |
| Highly-multiplexed barcode sequencing: an efficient method for parallel analysis of pooled samples AM Smith, LE Heisler, RP St. Onge, E Farias-Hesson, IM Wallace, ... Nucleic acids research 38 (13), e142-e142, 2010 | 269 | 2010 |
| Quantitative CRISPR interference screens in yeast identify chemical-genetic interactions and new rules for guide RNA design JD Smith, S Suresh, U Schlecht, M Wu, O Wagih, G Peltz, RW Davis, ... Genome biology 17, 1-16, 2016 | 223 | 2016 |
| An integrated platform of genomic assays reveals small-molecule bioactivities S Hoon, A M Smith, IM Wallace, S Suresh, M Miranda, E Fung, M Proctor, ... Nature chemical biology 4 (8), 498-506, 2008 | 218 | 2008 |
| HEx: A heterologous expression platform for the discovery of fungal natural products CJB Harvey, M Tang, U Schlecht, J Horecka, CR Fischer, HC Lin, J Li, ... Science advances 4 (4), eaar5459, 2018 | 212 | 2018 |
| Genome-wide requirements for resistance to functionally distinct DNA-damaging agents W Lee, RP St. Onge, M Proctor, P Flaherty, MI Jordan, AP Arkin, RW Davis, ... PLoS genetics 1 (2), e24, 2005 | 194 | 2005 |
| The human G2 checkpoint control protein hRAD9 is a nuclear phosphoprotein that forms complexes with hRAD1 and hHUS1 RPS Onge, CM Udell, R Casselman, S Davey Molecular Biology of the Cell 10 (6), 1985-1995, 1999 | 174 | 1999 |
| Multiplexed precision genome editing with trackable genomic barcodes in yeast KR Roy, JD Smith, SC Vonesch, G Lin, CS Tu, AR Lederer, A Chu, ... Nature biotechnology 36 (6), 512-520, 2018 | 155 | 2018 |
| A role for the phosphorylation of hRad9 in checkpoint signaling RPS Onge, BDA Besley, JL Pelley, S Davey Journal of Biological Chemistry 278 (29), 26620-26628, 2003 | 125 | 2003 |
| Gene Annotation and Drug Target Discovery in Candida albicans with a Tagged Transposon Mutant Collection J Oh, E Fung, U Schlecht, RW Davis, G Giaever, RP St. Onge, ... PLoS pathogens 6 (10), e1001140, 2010 | 121 | 2010 |
| A yeast-based assay identifies drugs active against human mitochondrial disorders E Couplan, RS Aiyar, R Kucharczyk, A Kabala, N Ezkurdia, J Gagneur, ... Proceedings of the National Academy of Sciences 108 (29), 11989-11994, 2011 | 100 | 2011 |
| Yeast chemical genomics and drug discovery: an update S Hoon, RPS Onge, G Giaever, C Nislow Trends in pharmacological sciences 29 (10), 499-504, 2008 | 99 | 2008 |
| Knocking out multigene redundancies via cycles of sexual assortment and fluorescence selection Y Suzuki, RPS Onge, R Mani, OD King, A Heilbut, VM Labunskyy, ... Nature methods 8 (2), 159-164, 2011 | 95 | 2011 |
| Multiplex assay for condition-dependent changes in protein–protein interactions U Schlecht, M Miranda, S Suresh, RW Davis, RP St. Onge Proceedings of the National Academy of Sciences 109 (23), 9213-9218, 2012 | 81 | 2012 |
| Distinct patterns of Cas9 mismatch tolerance in vitro and in vivo BXH Fu, RP St. Onge, AZ Fire, JD Smith Nucleic Acids Research 44 (11), 5365-5377, 2016 | 77 | 2016 |
