Alastair Davies
Alastair Davies
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The Master Neural Transcription Factor BRN2 Is an Androgen Receptor–Suppressed Driver of Neuroendocrine Differentiation in Prostate Cancer
JL Bishop, D Thaper, S Vahid, A Davies, K Ketola, H Kuruma, R Jama, ...
Cancer Discovery 7 (1), 54-71, 2017
Cellular plasticity and the neuroendocrine phenotype in prostate cancer
AH Davies, H Beltran, A Zoubeidi
Nature Reviews Urology 15 (5), 271-286, 2018
Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus
DG Simmons, S Rawn, A Davies, M Hughes, JC Cross
BMC genomics 9 (1), 1-20, 2008
Y-box binding protein-1 induces the expression of CD44 and CD49f leading to enhanced self-renewal, mammosphere growth, and drug resistance
K To, A Fotovati, KM Reipas, JH Law, K Hu, J Wang, A Astanehe, ...
Cancer research 70 (7), 2840-2851, 2010
Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells
AL Stratford, CJ Fry, C Desilets, AH Davies, YY Cho, Y Li, Z Dong, ...
Breast Cancer Research 10 (6), 1-12, 2008
Profiling YB-1 target genes uncovers a new mechanism for MET receptor regulation in normal and malignant human mammary cells
MR Finkbeiner, A Astanehe, K To, A Fotovati, AH Davies, Y Zhao, H Jiang, ...
Oncogene 28 (11), 1421-1431, 2009
Small interfering RNA library screen of human kinases and phosphatases identifies polo-like kinase 1 as a promising new target for the treatment of pediatric rhabdomyosarcomas
K Hu, C Lee, D Qiu, A Fotovati, A Davies, S Abu-Ali, D Wai, ER Lawlor, ...
Molecular cancer therapeutics 8 (11), 3024-3035, 2009
Biological evolution of castration-resistant prostate cancer
A Davies, V Conteduca, A Zoubeidi, H Beltran
European urology focus 5 (2), 147-154, 2019
YB-1 evokes susceptibility to cancer through cytokinesis failure, mitotic dysfunction and HER2 amplification
AH Davies, I Barrett, MR Pambid, K Hu, AL Stratford, S Freeman, ...
Oncogene 30 (34), 3649-3660, 2011
Regulation of tumor cell plasticity by the androgen receptor in prostate cancer
JL Bishop, A Davies, K Ketola, A Zoubeidi
Endocr Relat Cancer 22 (3), R165-R182, 2015
The epigenetic and transcriptional landscape of neuroendocrine prostate cancer
A Davies, A Zoubeidi, LA Selth
Endocrine-Related Cancer 27 (2), R35-R50, 2020
An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer
A Davies, S Nouruzi, D Ganguli, T Namekawa, D Thaper, S Linder, ...
Nature Cell Biology 23 (9), 1023-1034, 2021
YB‐1 Transforms human mammary epithelial cells through chromatin remodeling leading to the development of basal‐like breast cancer
AH Davies, KM Reipas, MR Pambid, R Berns, AL Stratford, A Fotovati, ...
Stem cells 32 (6), 1437-1450, 2014
Inhibition of RSK with the novel small-molecule inhibitor LJI308 overcomes chemoresistance by eliminating cancer stem cells
AH Davies, K Reipas, K Hu, R Berns, N Firmino, AL Stratford, SE Dunn
Oncotarget 6 (24), 20570, 2015
Targeting Prostate Cancer Subtype 1 by Forkhead Box M1 Pathway Inhibition
K Ketola, RSN Munuganti, A Davies, KM Nip, JL Bishop, A Zoubeidi
Clinical Cancer Research 23 (22), 6923-6933, 2017
Patient-derived xenografts: A platform for accelerating translational research in prostate cancer
AH Davies, Y Wang, A Zoubeidi
Molecular and cellular endocrinology 462, 17-24, 2018
Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction.
M Eaton, AH Davies, J Devine, X Zhao, DG Simmons, E Maríusdóttir, ...
PloS one 15 (1), e0226735, 2020
CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer
M Ahmed, F Soares, JH Xia, Y Yang, J Li, H Guo, P Su, Y Tian, HJ Lee, ...
Nature communications 12 (1), 1-15, 2021
YB-1 drives preneoplastic progression: Insight into opportunities for cancer prevention
AH Davies, SE Dunn
Oncotarget 2 (5), 401, 2011
The Androgen Receptor Bridges Stem Cell-Associated Signaling Nodes in Prostate Stem Cells
AH Davies, A Zoubeidi
Stem cells international 2016, 2016
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