Discovery and structure-activity relationship studies of 2-benzylidene-2, 3-dihydro-1H-inden-1-one and benzofuran-3 (2H)-one derivatives as a novel class of potential … TM Kadayat, S Banskota, P Gurung, G Bist, TBT Magar, A Shrestha, ... European Journal of Medicinal Chemistry 137, 575-597, 2017 | 45 | 2017 |
Hydroxylated 2, 4-diphenyl indenopyridine derivatives as a selective non-intercalative topoisomerase IIα catalytic inhibitor TM Kadayat, C Park, KY Jun, TBT Magar, G Bist, HY Yoo, Y Kwon, ES Lee European Journal of Medicinal Chemistry 90, 302-314, 2015 | 41 | 2015 |
Topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study of dihydroxylated 2, 6-diphenyl-4-aryl pyridines R Karki, C Song, TM Kadayat, TBT Magar, G Bist, A Shrestha, Y Na, ... Bioorganic & medicinal chemistry 23 (13), 3638-3654, 2015 | 37 | 2015 |
Inhibition of LPS-stimulated ROS production by fluorinated and hydroxylated chalcones in RAW 264.7 macrophages with structure-activity relationship study G Bist, NT Pun, TBT Magar, A Shrestha, HJ Oh, A Khakurel, PH Park, ... Bioorganic & medicinal chemistry letters 27 (5), 1205-1209, 2017 | 36 | 2017 |
Rational design, synthesis, and evaluation of novel 2, 4-Chloro-and Hydroxy-Substituted diphenyl Benzofuro [3, 2-b] Pyridines: Non-intercalative catalytic topoisomerase I and … S Park, TBT Magar, TM Kadayat, HJ Lee, G Bist, A Shrestha, ES Lee, ... European Journal of Medicinal Chemistry 127, 318-333, 2017 | 32 | 2017 |
Novel 2-aryl-4-(4′-hydroxyphenyl)-5H-indeno [1, 2-b] pyridines as potent DNA non-intercalative topoisomerase catalytic inhibitors S Park, TM Kadayat, KY Jun, TBT Magar, G Bist, A Shrestha, ES Lee, ... European journal of medicinal chemistry 125, 14-28, 2017 | 30 | 2017 |
Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study of 2-phenyl-or hydroxylated 2-phenyl-4-aryl-5H-indeno [1, 2-b … TM Kadayat, C Song, S Shin, TBT Magar, G Bist, A Shrestha, P Thapa, ... Bioorganic & Medicinal Chemistry 23 (13), 3499-3512, 2015 | 28 | 2015 |
Design and synthesis of novel 2, 4-diaryl-5H-indeno [1, 2-b] pyridine derivatives, and their evaluation of topoisomerase inhibitory activity and cytotoxicity TM Kadayat, C Park, KY Jun, TBT Magar, G Bist, HY Yoo, Y Kwon, ES Lee Bioorganic & Medicinal Chemistry 23 (1), 160-173, 2015 | 28 | 2015 |
Design and synthesis of conformationally constrained hydroxylated 4-phenyl-2-aryl chromenopyridines as novel and selective topoisomerase II-targeted antiproliferative agents P Thapa, KY Jun, TM Kadayat, C Park, Z Zheng, TBT Magar, G Bist, ... Bioorganic & Medicinal Chemistry 23 (19), 6454-6466, 2015 | 26 | 2015 |
Synthesis and SAR study of new hydroxy and chloro-substituted 2, 4-diphenyl 5H-chromeno [4, 3-b] pyridines as selective topoisomerase IIα-targeting anticancer agents TBT Magar, SH Seo, TM Kadayat, H Jo, A Shrestha, G Bist, P Katila, ... Bioorganic & medicinal chemistry 26 (8), 1909-1919, 2018 | 24 | 2018 |
Design, synthesis, and structure-activity relationship study of halogen containing 2-benzylidene-1-indanone derivatives for inhibition of LPS-stimulated ROS production in RAW … A Shrestha, HJ Oh, MJ Kim, NT Pun, TBT Magar, G Bist, H Choi, PH Park, ... European Journal of Medicinal Chemistry 133, 121-138, 2017 | 24 | 2017 |
2-Chlorophenyl-substituted benzofuro [3, 2-b] pyridines with enhanced topoisomerase inhibitory activity: The role of the chlorine substituent TBT Magar, TM Kadayat, HJ Lee, S Park, G Bist, A Shrestha, Y Kwon, ... Bioorganic & Medicinal Chemistry Letters 27 (15), 3279-3283, 2017 | 23 | 2017 |
Dihydroxylated 2, 6-diphenyl-4-chlorophenylpyridines: Topoisomerase I and IIα dual inhibitors with DNA non-intercalative catalytic activity G Bist, S Park, C Song, TBT Magar, A Shrestha, Y Kwon, ES Lee European Journal of Medicinal Chemistry 133, 69-84, 2017 | 22 | 2017 |
A new series of 2-phenol-4-aryl-6-chlorophenyl pyridine derivatives as dual topoisomerase I/II inhibitors: Synthesis, biological evaluation and 3D-QSAR study R Karki, KY Jun, TM Kadayat, S Shin, TBT Magar, G Bist, A Shrestha, ... European Journal of Medicinal Chemistry 113, 228-245, 2016 | 21 | 2016 |
Patterns and perception of complementary and alternative medicine use by patients in western Nepal TM Kadayat, G Bist, A Parajuli, R Karki, A Kaundinnyayana, N Dhami Journal of Public Health 20, 297-303, 2012 | 20 | 2012 |
Effect of chlorine substituent on cytotoxic activities: Design and synthesis of systematically modified 2, 4-diphenyl-5H-indeno [1, 2-b] pyridines TM Kadayat, S Park, KY Jun, TBT Magar, G Bist, A Shrestha, Y Na, ... Bioorganic & Medicinal Chemistry Letters 26 (7), 1726-1731, 2016 | 17 | 2016 |
Design, synthesis, biological evaluation, structure-activity relationship study, and mode of action of 2-phenol-4, 6-dichlorophenyl-pyridines A Shrestha, S Park, S Shin, TM Kadayat, G Bist, P Katila, Y Kwon, ES Lee Bioorganic Chemistry 79, 1-18, 2018 | 16 | 2018 |
Synthesis and biological evaluation of 2-phenol-4-chlorophenyl-6-aryl pyridines as topoisomerase II inhibitors and cytotoxic agents P Thapa, TM Kadayat, S Park, S Shin, TBT Magar, G Bist, A Shrestha, ... Bioorganic chemistry 66, 145-159, 2016 | 16 | 2016 |
Synthesis and biological evaluation of pyridine-linked indanone derivatives: Potential agents for inflammatory bowel disease TM Kadayat, S Banskota, G Bist, P Gurung, TBT Magar, A Shrestha, ... Bioorganic & Medicinal Chemistry Letters 28 (14), 2436-2441, 2018 | 13 | 2018 |
Identification of new halogen-containing 2, 4-diphenyl indenopyridin-5-one derivative as a boosting agent for the anticancer responses of clinically available topoisomerase … SY Hwang, A Shrestha, S Park, G Bist, S Kunwar, TM Kadayat, H Jang, ... European Journal of Medicinal Chemistry 227, 113916, 2022 | 7 | 2022 |