Florian Grebien
Florian Grebien
Institute for Medical Biochemistry - University of Veterinary Medicine Vienna
Verified email at
Cited by
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Stat5 is indispensable for the maintenance of bcr/abl‐positive leukaemia
A Hoelbl, C Schuster, B Kovacic, B Zhu, M Wickre, MA Hoelzl, S Fajmann, ...
EMBO molecular medicine 2 (3), 98-110, 2010
Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia
F Grebien, M Vedadi, M Getlik, R Giambruno, A Grover, R Avellino, ...
Nature chemical biology 11 (8), 571-578, 2015
CD14 is a coreceptor of Toll-like receptors 7 and 9
CL Baumann, IM Aspalter, O Sharif, A Pichlmair, S Blüml, F Grebien, ...
Journal of Experimental Medicine 207 (12), 2689-2701, 2010
Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation
P Filippakopoulos, M Kofler, O Hantschel, GD Gish, F Grebien, E Salah, ...
Cell 134 (5), 793-803, 2008
JAK-STAT signaling in cancer: From cytokines to non-coding genome
J Pencik, HTT Pham, J Schmoellerl, T Javaheri, M Schlederer, Z Culig, ...
Cytokine 87, 26-36, 2016
BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia
O Hantschel, W Warsch, E Eckelhart, I Kaupe, F Grebien, KU Wagner, ...
Nature chemical biology 8 (3), 285-293, 2012
A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain
J Wojcik, O Hantschel, F Grebien, I Kaupe, KL Bennett, J Barkinge, ...
Nature structural & molecular biology 17 (4), 519-527, 2010
Evidence for a size-sensing mechanism in animal cells
H Dolznig, F Grebien, T Sauer, H Beug, EW Müllner
Nature cell biology 6 (9), 899-905, 2004
STAT3 regulated ARF expression suppresses prostate cancer metastasis
J Pencik, M Schlederer, W Gruber, C Unger, SM Walker, A Chalaris, ...
Nature communications 6 (1), 7736, 2015
Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis
F Grebien, O Hantschel, J Wojcik, I Kaupe, B Kovacic, AM Wyrzucki, ...
Cell 147 (2), 306-319, 2011
Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2
F Grebien, MA Kerenyi, B Kovacic, T Kolbe, V Becker, H Dolznig, K Pfeffer, ...
Blood, The Journal of the American Society of Hematology 111 (9), 4511-4522, 2008
Pharmacologic inhibition of STAT5 in acute myeloid leukemia
B Wingelhofer, B Maurer, EC Heyes, AA Cumaraswamy, A Berger-Becvar, ...
Leukemia 32 (5), 1135-1146, 2018
Nilotinib-induced vasculopathy: identification of vascular endothelial cells as a primary target site
E Hadzijusufovic, K Albrecht-Schgoer, K Huber, G Hoermann, F Grebien, ...
Leukemia 31 (11), 2388-2397, 2017
Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1
MA Kerenyi, F Grebien, H Gehart, M Schifrer, M Artaker, B Kovacic, ...
Blood, The Journal of the American Society of Hematology 112 (9), 3878-3888, 2008
HBO1 is required for the maintenance of leukaemia stem cells
L MacPherson, J Anokye, MM Yeung, EYN Lam, YC Chan, CF Weng, ...
Nature 577 (7789), 266-270, 2020
Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML
GE Winter, U Rix, SM Carlson, KV Gleixner, F Grebien, M Gridling, ...
Nature chemical biology 8 (11), 905-912, 2012
The growing arsenal of ATP-competitive and allosteric inhibitors of BCR–ABL
O Hantschel, F Grebien, G Superti-Furga
Cancer research 72 (19), 4890-4895, 2012
STAT5BN642H is a driver mutation for T cell neoplasia
HTT Pham, B Maurer, M Prchal-Murphy, R Grausenburger, ...
The Journal of clinical investigation 128 (1), 387-401, 2018
Erythroid progenitor renewal versus differentiation: genetic evidence for cell autonomous, essential functions of EpoR, Stat5 and the GR
H Dolznig, F Grebien, EM Deiner, K Stangl, A Kolbus, B Habermann, ...
Oncogene 25 (20), 2890-2900, 2006
Biomolecular condensation of NUP98 fusion proteins drives leukemogenic gene expression
S Terlecki-Zaniewicz, T Humer, T Eder, J Schmoellerl, E Heyes, ...
Nature structural & molecular biology 28 (2), 190-201, 2021
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