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Jun Jacob Hu
Jun Jacob Hu
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Verified email at childrens.harvard.edu - Homepage
Title
Cited by
Cited by
Year
FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation
JJ Hu, X Liu, S Xia, Z Zhang, Y Zhang, J Zhao, J Ruan, X Luo, X Lou, ...
Nature immunology 21 (7), 736-745, 2020
6432020
Fluorescent probe HKSOX-1 for imaging and detection of endogenous superoxide in live cells and in vivo
JJ Hu, NK Wong, S Ye, X Chen, MY Lu, AQ Zhao, Y Guo, ACH Ma, ...
Journal of the American Chemical Society 137 (21), 6837-6843, 2015
2492015
HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation
VG Magupalli, R Negro, Y Tian, AV Hauenstein, G Di Caprio, W Skillern, ...
Science 369 (6510), eaas8995, 2020
2462020
Molecular imaging of peroxynitrite with HKGreen-4 in live cells and tissues
T Peng, NK Wong, X Chen, YK Chan, DHH Ho, Z Sun, JJ Hu, J Shen, ...
Journal of the American Chemical Society 136 (33), 11728-11734, 2014
2462014
HKOCl-2 series of green BODIPY-based fluorescent probes for hypochlorous acid detection and imaging in live cells
JJ Hu, NK Wong, Q Gu, X Bai, S Ye, D Yang
Organic letters 16 (13), 3544-3547, 2014
1862014
HKOCl-3: a fluorescent hypochlorous acid probe for live-cell and in vivo imaging and quantitative application in flow cytometry and a 96-well microplate assay
JJ Hu, NK Wong, MY Lu, X Chen, S Ye, AQ Zhao, P Gao, RYT Kao, ...
Chemical science 7 (3), 2094-2099, 2016
1452016
Chain Collapse and Revival Thermodynamics of Poly(N-isopropylacrylamide) Hydrogel
S Sun, J Hu, H Tang, P Wu
The Journal of Physical Chemistry B 114 (30), 9761-9770, 2010
1252010
Small-molecule-based fluorescent sensors for selective detection of reactive oxygen species in biological systems
X Bai, KKH Ng, JJ Hu, S Ye, D Yang
Annual Review of Biochemistry 88, 605-633, 2019
772019
Tandem payne/dakin reaction: A new strategy for hydrogen peroxide detection and molecular imaging
S Ye, JJ Hu, D Yang
Angewandte Chemie 130 (32), 10330-10334, 2018
682018
Spectral interpretation of thermally irreversible recovery of poly (N-isopropylacrylamide-co-acrylic acid) hydrogel
S Sun, J Hu, H Tang, P Wu
Physical Chemistry Chemical Physics 13 (11), 5061-5067, 2011
532011
Fluorescent probes for in vitro and in vivo quantification of hydrogen peroxide
S Ye, JJ Hu, QA Zhao, D Yang
Chemical Science 11 (44), 11989-11997, 2020
442020
The NK cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells
S Sen Santara, DJ Lee, Â Crespo, JJ Hu, C Walker, X Ma, Y Zhang, ...
Nature 616 (7956), 348-356, 2023
422023
Fluorescent probes for HOCl imaging
JJ Hu, S Ye, D Yang
Israel Journal of Chemistry 57 (3-4), 251-258, 2017
352017
Identification of pyroptosis inhibitors that target a reactive cysteine in gasdermin D
JJ Hu, X Liu, J Zhao, S Xia, J Ruan, X Luo, J Kim, J Lieberman, H Wu
BioRxiv, 365908, 2018
312018
SPARCLE, a p53-induced lncRNA, controls apoptosis after genotoxic stress by promoting PARP-1 cleavage
KF Meza-Sosa, R Miao, F Navarro, Z Zhang, Y Zhang, JJ Hu, ...
Molecular cell 82 (4), 785-802. e10, 2022
292022
HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation. Science. 369: eaas8995
VG Magupalli, R Negro, Y Tian, AV Hauenstein, G Di Caprio, W Skillern, ...
82020
Diarylether-based fluorogenic probes for detection of hypochlorous acid or hydroxyl radical
D Yang, J Hu, NK Wong, X Bai
US Patent 10,684,294, 2020
32020
The NK receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells
SS Santara, Â Crespo, DJ Lee, JJ Hu, Y Zhang, S Chowdhury, ...
bioRxiv, 2021.10. 31.466654, 2021
22021
Bistrifilate-based fluorogenic probes for detection of superoxide anion radical
D Yang, NK Wong, J Hu
US Patent 11,585,819, 2023
2023
Compounds for inhibition of inflammation
H Wu, J Lieberman, J Hu, X Liu
US Patent App. 17/255,092, 2021
2021
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Articles 1–20