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Sean Egan
Sean Egan
Cell Biology Program - The Hospital for Sick Children
Verified email at sickkids.ca
Title
Cited by
Cited by
Year
Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation
SE Egan, BW Giddings, MW Brooks, L Buday, AM Sizeland, RA Weinberg
Nature 363 (6424), 45-51, 1993
16031993
High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival
M Reedijk, S Odorcic, L Chang, H Zhang, N Miller, DR McCready, ...
Cancer research. 65 (18), 8530-7, 2005
9422005
The pathway to signal achievement.
SE Egan, RA Weinberg
Nature 365 (6449), 1993
8061993
A complex of Grb2 adaptor protein, Sos exchange factor, and a 36-kDa membrane-bound tyrosine phosphoprotein is implicated in ras activation in T cells.
L Buday, SE Egan, PR Viciana, DA Cantrell, J Downward
Journal of Biological Chemistry 269 (12), 9019-9023, 1994
3291994
The EH and SH3 domain Ese proteins regulate endocytosis by linking to dynamin and Eps15
AS Sengar, W Wang, J Bishay, S Cohen, SE Egan
The EMBO journal 18 (5), 1159-71, 1999
2731999
High-level JAG1 mRNA and protein predict poor outcome in breast cancer
BC Dickson, AM Mulligan, H Zhang, G Lockwood, FP O'Malley, SE Egan, ...
Modern pathology : an official journal of the United States and Canadian …, 2007
2692007
Activation of Notch signaling in human colon adenocarcinoma
M Reedijk, S Odorcic, H Zhang, R Chetty, C Tennert, BC Dickson, ...
International journal of oncology 33 (6), 1223-9, 2008
2592008
Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1
U Koch, TA Lacombe, D Holland, JL Bowman, BL Cohen, SE Egan, ...
Immunity 15 (2), 225-236, 2001
2392001
Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts
AD Pfefferle, JI Herschkowitz, J Usary, JC Harrell, BT Spike, JR Adams, ...
Genome biology 14, 1-16, 2013
2342013
Notch signaling in mammary development and oncogenesis.
R Callahan, SE Egan
Journal of mammary gland biology and neoplasia 9 (2), 145-163, 2004
2042004
Expression of H-ras Correlates with Metastatic Potential: Evidence for Direct Regulation of the Metastatic Phenotype in 10T1/2 and NIH 3T3 Cells
SE Egan, GA McClarty, L Jarolim, JA Wright, I Spiro, G Hager, ...
Molecular and cellular biology 7 (2), 830-837, 1987
1951987
JAG1 expression is associated with a basal phenotype and recurrence in lymph node-negative breast cancer.
M Reedijk, D Pinnaduwage, BC Dickson, AM Mulligan, H Zhang, SB Bull, ...
Breast cancer research and treatment 111 (3), 439-48, 2008
1882008
Fringe boundaries coincide with Notch-dependent patterning centres in mammals and alter Notch-dependent development in Drosophila
HLSEE B. Cohen, A. Bashirullah, Lina Dagnino, C. Campbell, Bill Fisher, C. C ...
Nature Genetics 16 (3), 283-288, 1997
1871997
Cysteine proteinase cathepsin L expression correlates closely with the metastatic potential of H-ras-transformed murine fibroblasts.
DT Denhardt, AH Greenberg, SE Egan, RT Hamilton, JA Wright
Oncogene 2 (1), 55-59, 1987
1861987
Notch receptors, partners and regulators: from conserved domains to powerful functions
SE Egan, B St-Pierre, CC Leow
Protein Modules in Signal Transduction, 273-324, 1998
1721998
Transformation by oncogenes encoding protein kinases induces the metastatic phenotype
SE Egan, JA Wright, L Jarolim, K Yanagihara, RH Bassin, AH Greenberg
Science 238 (4824), 202-205, 1987
1651987
Cooperation between Pik3ca and p53 mutations in mouse mammary tumor formation
JR Adams, K Xu, JC Liu, NM Agamez, AJ Loch, RG Wong, W Wang, ...
Cancer Research 71 (7), 2706-17, 2011
1542011
Lunatic and manic fringe cooperatively enhance marginal zone B cell precursor competition for delta-like 1 in splenic endothelial niches
JB Tan, K Xu, K Cretegny, I Visan, JS Yuan, SE Egan, CJ Guidos
Immunity 30 (2), 254-63, 2009
1532009
The Hand1, Stra13 and Gcm1 transcription factors override FGF signaling to promote terminal differentiation of trophoblast stem cells.
M Hughes, N Dobric, IC Scott, L Su, M Starovic, B St-Pierre, SE Egan, ...
Developmental biology 271 (1), 26-37, 2004
1522004
Expression of notch receptors, notch ligands, and fringe genes in hematopoiesis
N Singh, RA Phillips, NN Iscove, SE Egan
Experimental hematology 28 (5), 527-534, 2000
1472000
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