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Chun Chen
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Dynamic modelling of oestrogen signalling and cell fate in breast cancer cells
JJ Tyson, WT Baumann, C Chen, A Verdugo, I Tavassoly, Y Wang, ...
Nature Reviews Cancer 11 (7), 523-532, 2011
2202011
Myeloid cell-derived inducible nitric oxide synthase suppresses M1 macrophage polarization
G Lu, R Zhang, S Geng, L Peng, P Jayaraman, C Chen, F Xu, J Yang, Q Li, ...
Nature communications 6 (1), 6676, 2015
2182015
The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis
S Geng, K Chen, R Yuan, L Peng, U Maitra, N Diao, C Chen, Y Zhang, ...
Nature communications 7 (1), 13436, 2016
1792016
Modeling of the role of a Bax-activation switch in the mitochondrial apoptosis decision
C Chen, J Cui, H Lu, R Wang, S Zhang, P Shen
Biophysical journal 92 (12), 4304-4315, 2007
1302007
Identification of human liver mitochondrial aldehyde dehydrogenase as a potential target for microcystin-LR
T Chen, J Cui, Y Liang, X Xin, DO Young, C Chen, P Shen
Toxicology 220 (1), 71-80, 2006
912006
Two independent positive feedbacks and bistability in the Bcl-2 apoptotic switch
J Cui, C Chen, H Lu, T Sun, P Shen
PLoS One 3 (1), e1469, 2008
822008
Upstream process intensification and continuous manufacturing
C Chen, HE Wong, CT Goudar
Current Opinion in Chemical Engineering 22, 191-198, 2018
752018
Modeling the role of p53 pulses in DNA damage-induced cell death decision
T Sun, C Chen, Y Wu, S Zhang, J Cui, P Shen
BMC bioinformatics 10, 1-12, 2009
652009
Endoplasmic reticulum stress, the unfolded protein response, and gene network modeling in antiestrogen resistant breast cancer
R Clarke, AN Shajahan, Y Wang, JJ Tyson, RB Riggins, LM Weiner, ...
Hormone Molecular Biology and Clinical Investigation, 2011
642011
Reprogramming macrophage orientation by microRNA 146b targeting transcription factor IRF5
L Peng, H Zhang, Y Hao, F Xu, J Yang, R Zhang, G Lu, Z Zheng, M Cui, ...
EBioMedicine 14, 83-96, 2016
602016
Robustness analysis identifies the plausible model of the Bcl-2 apoptotic switch
C Chen, J Cui, W Zhang, P Shen
FEBS letters 581 (26), 5143-5150, 2007
592007
Interferon regulatory factor-1 signaling regulates the switch between autophagy and apoptosis to determine breast cancer cell fate
JL Schwartz-Roberts, KL Cook, C Chen, AN Shajahan-Haq, M Axelrod, ...
Cancer research 75 (6), 1046-1055, 2015
372015
Modeling the estrogen receptor to growth factor receptor signaling switch in human breast cancer cells
C Chen, WT Baumann, R Clarke, JJ Tyson
FEBS letters 587 (20), 3327-3334, 2013
372013
Assuring Clonality on the Beacon Digital Cell Line Development Platform
K Le, C Tan, H Le, J Tat, E Zasadzinska, J Diep, R Zastrow, C Chen, ...
Biotechnology Journal, 2019
362019
Mathematical models of the transitions between endocrine therapy responsive and resistant states in breast cancer
C Chen, WT Baumann, J Xing, L Xu, R Clarke, JJ Tyson
Journal of The Royal Society Interface 11 (96), 20140206, 2014
332014
Integration of systems biology in cell line and process development for biopharmaceutical manufacturing
C Chen, H Le, CT Goudar
Biochemical Engineering Journal 107, 11-17, 2016
232016
An automated RNA‐Seq analysis pipeline to identify and visualize differentially expressed genes and pathways in CHO cells
C Chen, H Le, CT Goudar
Biotechnology progress 31 (5), 1150-1162, 2015
192015
From Chemostats to High‐Density Perfusion: The Progression of Continuous Mammalian Cell Cultivation
HE Wong, C Chen, H Le, CT Goudar
Journal of Chemical Technology & Biotechnology, 2021
162021
Methods for Estimating the Probability of Clonality in Cell Line Development
C Chen, K Le, H Le, K Daris, N Soice, J Stevens, CT Goudar
Biotechnology Journal 15 (2), 1900289, 2020
152020
Transcription Dependent and Independent Roles of p53 in Apoptosis Regulation [J]
TZ Sun, C Chen, PP Shen
Chinese Journal of Cell Biology 3, 007, 2008
15*2008
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Articles 1–20