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Daniel Kulke
Daniel Kulke
Bayer Animal Health GmbH
Verified email at arcor.de
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Year
Caenorhabditis elegans in anthelmintic research–Old model, new perspectives
SR Hahnel, CM Dilks, I Heisler, EC Andersen, D Kulke
International journal for parasitology: drugs and drug resistance 14, 237-248, 2020
542020
Reprogramming the biosynthesis of cyclodepsipeptide synthetases to obtain new enniatins and beauvericins
S Zobel, S Boecker, D Kulke, D Heimbach, V Meyer, RD Süssmuth
ChemBioChem 17 (4), 283-287, 2016
522016
Dirofilaria immitis Microfilariae and Third-Stage Larvae Induce Canine NETosis Resulting in Different Types of Neutrophil Extracellular Traps
T Muñoz-Caro, I Conejeros, E Zhou, A Pikhovych, U Gärtner, ...
Frontiers in Immunology 9, 968, 2018
472018
Characterization of the Ca2+-Gated and Voltage-Dependent K+-Channel Slo-1 of Nematodes and Its Interaction with Emodepside
D Kulke, G von Samson-Himmelstjerna, SM Miltsch, AJ Wolstenholme, ...
PLoS neglected tropical diseases 8 (12), e3401, 2014
472014
Microfilariae trigger eosinophil extracellular DNA traps in a dectin-1-dependent manner
A Ehrens, B Lenz, AL Neumann, S Giarrizzo, JJ Reichwald, ...
Cell reports 34 (2), 2021
392021
Development of emodepside as a possible adulticidal treatment for human onchocerciasis—The fruit of a successful industrial–academic collaboration
J Krücken, L Holden-Dye, J Keiser, RK Prichard, S Townson, ...
PLoS Pathogens 17 (7), e1009682, 2021
382021
Emodepside has sex-dependent immobilizing effects on adult Brugia malayi due to a differentially spliced binding pocket in the RCK1 region of the SLO-1 K channel
SS Kashyap, S Verma, D Voronin, S Lustigman, D Kulke, AP Robertson, ...
PLoS Pathogens 15 (9), e1008041, 2019
322019
Efficacy evaluation of anthelmintic products against an infection with the canine hookworm (Ancylostoma caninum) isolate Worthy 4.1 F3P in dogs
PDJ Castro, A Mansour, S Charles, J Hostetler, T Settje, D Kulke, ...
International Journal for Parasitology: Drugs and Drug Resistance 13, 22-27, 2020
282020
Evaluation of the in vitro susceptibility of various filarial nematodes to emodepside
MP Hübner, S Townson, S Gokool, S Tagboto, MJ Maclean, GG Verocai, ...
International Journal for Parasitology: Drugs and Drug Resistance 17, 27-35, 2021
202021
Macrocyclic lactone anthelmintic-induced leukocyte binding to Dirofilaria immitis microfilariae: influence of the drug resistance status of the parasite
T Berrafato, R Coates, BJ Reaves, D Kulke, AJ Wolstenholme
International Journal for Parasitology: Drugs and Drug Resistance 10, 45-50, 2019
182019
Efficacy of cyclooctadepsipeptides and aminophenylamidines against larval, immature and mature adult stages of a parasitologically characterized trichurosis model in mice
D Kulke, J Krücken, A Harder, G von Samson-Himmelstjerna
PLoS Neglected Tropical Diseases 8 (2), e2698, 2014
172014
Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis
GS Bah, S Schneckener, SR Hahnel, NH Bayang, H Fieseler, ...
PLoS pathogens 17 (6), e1009601, 2021
152021
In vivo efficacy of the anthelmintic tribendimidine against the cestode Hymenolepis microstoma in a controlled laboratory trial
D Kulke, J Krücken, C Welz, G von Samson-Himmelstjerna, A Harder
Acta tropica 123 (2), 78-84, 2012
132012
In vitro efficacy of cyclooctadepsipepdtides and aminophenylamidines alone and in combination against third-stage larvae and adult worms of Nippostrongylus brasiliensis and …
D Kulke, J Krücken, J Demeler, A Harder, H Mehlhorn, ...
Parasitology research 112, 335-345, 2013
112013
Comparison of electrophysiological and motility assays to study anthelmintic effects in Caenorhabditis elegans
SR Hahnel, WM Roberts, I Heisler, D Kulke, JC Weeks
International Journal for Parasitology: Drugs and Drug Resistance 16, 174-187, 2021
102021
Comparison of the in vitro susceptibility to emodepside of microfilariae, third stage larvae and adult worms of related filarial nematodes
D Kulke, S Townson, D Bloemker, S Frohberger, S Specht, I Scandale, ...
Am J Trop Med Hyg 97 (5), 563, 2017
72017
In vivo efficacy of PF1022A and nicotinic acetylcholine receptor agonists alone and in combination against Nippostrongylus brasiliensis
D Kulke, J Kruecken, A Harder, R Krebber, K Fraatz, H Mehlhorn, ...
Parasitology 140 (10), 1252-1265, 2013
72013
Periodicity of Dirofilaria immitis in longterm infections.
C Evans, E Burkman, M Dzimianski, A Moorhead, M Savadelis, ...
Parasitology Research 116, 2017
62017
Nemacol is a small molecule inhibitor of C. elegans vesicular acetylcholine transporter with anthelmintic potential
S Harrington, J Pyche, AR Burns, T Spalholz, KT Ryan, RJ Baker, J Ching, ...
Nature Communications 14 (1), 1816, 2023
52023
Egg-laying and locomotory screens with C. elegans yield a nematode-selective small molecule stimulator of neurotransmitter release
S Harrington, JJ Knox, AR Burns, KL Choo, A Au, M Kitner, C Haeberli, ...
Communications biology 5 (1), 865, 2022
52022
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