Johannes W. Bigenzahn
Johannes W. Bigenzahn
Medical University Vienna :: CeMM Research Center for Molecular Medicine, Vienna
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Gene essentiality and synthetic lethality in haploid human cells
VA Blomen, P Májek, LT Jae, JW Bigenzahn, J Nieuwenhuis, J Staring, ...
Science 350 (6264), 1092-1096, 2015
SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1
M Rebsamen, L Pochini, T Stasyk, MEG de Araújo, M Galluccio, ...
Nature 519 (7544), 477-481, 2015
A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis
A Fauster, M Rebsamen, KVM Huber, JW Bigenzahn, A Stukalov, ...
Cell death & disease 6 (5), e1767-e1767, 2015
Image-based ex-vivo drug screening for patients with aggressive haematological malignancies: interim results from a single-arm, open-label, pilot study
B Snijder, GI Vladimer, N Krall, K Miura, AS Schmolke, C Kornauth, ...
The Lancet Haematology 4 (12), e595-e606, 2017
LZTR1 is a regulator of RAS ubiquitination and signaling
JW Bigenzahn, GM Collu, F Kartnig, M Pieraks, GI Vladimer, LX Heinz, ...
Science 362 (6419), 1171-1177, 2018
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7–9
LX Heinz, JE Lee, U Kapoor, F Kartnig, V Sedlyarov, K Papakostas, ...
Nature, 1-7, 2020
JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia
K Boztug, PM Järvinen, E Salzer, T Racek, S Mönch, W Garncarz, ...
Nature genetics 46 (9), 1021-1027, 2014
Recent advances in combinatorial drug screening and synergy scoring
T Pemovska, JW Bigenzahn, G Superti-Furga
Current opinion in pharmacology 42, 102-110, 2018
The Bicarbonate Transporter SLC4A7 Plays a Key Role in Macrophage Phagosome Acidification
V Sedlyarov, R Eichner, E Girardi, P Essletzbichler, U Goldmann, ...
Cell host & microbe 23 (6), 766-774. e5, 2018
Global survey of the immunomodulatory potential of common drugs
GI Vladimer, B Snijder, N Krall, JW Bigenzahn, KVM Huber, CH Lardeau, ...
Nature chemical biology 13 (6), 681, 2017
The RNA‐binding protein HuR/ELAVL1 regulates IFN‐β mRNA abundance and the type I IFN response
B Herdy, T Karonitsch, GI Vladimer, CSH Tan, A Stukalov, C Trefzer, ...
European journal of immunology 45 (5), 1500-1511, 2015
A time-resolved molecular map of the macrophage response to VSV infection
RK Kandasamy, GI Vladimer, B Snijder, AC Müller, M Rebsamen, ...
NPJ systems biology and applications 2 (1), 1-12, 2016
Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking
A Fauster, M Rebsamen, KL Willmann, A César-Razquin, E Girardi, ...
Cell Death & Differentiation 26 (6), 1138-1155, 2019
An inducible retroviral expression system for tandem affinity purification mass-spectrometry-based proteomics identifies mixed lineage kinase domain-like protein (MLKL) as an …
JW Bigenzahn, A Fauster, M Rebsamen, RK Kandasamy, S Scorzoni, ...
Molecular & Cellular Proteomics 15 (3), 1139-1150, 2016
Identifying kinase substrates via a heavy ATP kinase assay and quantitative mass spectrometry
AC Müller, R Giambruno, J Weißer, P Májek, A Hofer, JW Bigenzahn, ...
Scientific reports 6, 28107, 2016
The effect of resveratrol in combination with irradiation and chemotherapy
G Heiduschka, C Lill, R Seemann, M Brunner, R Schmid, R Houben, ...
Strahlentherapie und Onkologie 190 (1), 75-80, 2014
Resveratrol synergistically enhances the effect of etoposide in HNSCC cell lines
G Heiduschka, J Bigenzahn, M Brunner, D Thurnher
Acta oto-laryngologica 134 (10), 1071-1078, 2014
Evaluation of Polo‐like kinase 1 as a potential therapeutic target in Merkel cell carcinoma
L Kadletz, J Bigenzahn, D Thurnher, I Stanisz, BM Erovic, S Schneider, ...
Head & neck 38 (S1), E1918-E1925, 2016
Deficiency Of JAGN1 Causes Severe Congenital Neutropenia Associated With Defective Secretory Pathway and Aberrant Myeloid Cell Homeostasis
K Boztug, PM Järvinen, E Salzer, T Racek, S Mönch, W Garncarz, ...
Blood, The Journal of the American Society of Hematology 122 (21), 439-439, 2013
Abstract A08: Genetic drug resistance screen identifies LZTR1 as regulator of RAS ubiquitination and signaling
JW Bigenzahn, GM Collu, F Kartnig, M Pieraks, GI Vladimer, LX Heinz, ...
Molecular Cancer Research 18 (5 Supplement), A08-A08, 2020
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