Directed evolution drives the next generation of biocatalysts NJ Turner Nature chemical biology 5 (8), 567-573, 2009 | 957 | 2009 |
Biocatalysis EL Bell, W Finnigan, SP France, AP Green, MA Hayes, LJ Hepworth, ... Nature Reviews Methods Primers 1 (1), 1-21, 2021 | 517 | 2021 |
Biocatalytic approaches to the synthesis of enantiomerically pure chiral amines D Ghislieri, NJ Turner Topics in Catalysis 57, 284-300, 2014 | 477 | 2014 |
Carboxylic acid reductase is a versatile enzyme for the conversion of fatty acids into fuels and chemical commodities MK Akhtar, NJ Turner, PR Jones Proceedings of the National Academy of Sciences 110 (1), 87-92, 2013 | 430 | 2013 |
Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades FG Mutti, T Knaus, NS Scrutton, M Breuer, NJ Turner Science 349 (6255), 1525-1529, 2015 | 423 | 2015 |
Biocatalytic retrosynthesis NJ Turner, E O'reilly Nature chemical biology 9 (5), 285-288, 2013 | 404 | 2013 |
Constructing biocatalytic cascades: in vitro and in vivo approaches to de novo multi-enzyme pathways SP France, LJ Hepworth, NJ Turner, SL Flitsch Acs Catalysis 7 (1), 710-724, 2017 | 400 | 2017 |
Extending the application of biocatalysis to meet the challenges of drug development PN Devine, RM Howard, R Kumar, MP Thompson, MD Truppo, NJ Turner Nature Reviews Chemistry 2 (12), 409-421, 2018 | 391 | 2018 |
Engineering an enantioselective amine oxidase for the synthesis of pharmaceutical building blocks and alkaloid natural products D Ghislieri, AP Green, M Pontini, SC Willies, I Rowles, A Frank, G Grogan, ... Journal of the American Chemical Society 135 (29), 10863-10869, 2013 | 391 | 2013 |
Synthetic cascades are enabled by combining biocatalysts with artificial metalloenzymes V Köhler, YM Wilson, M Dürrenberger, D Ghislieri, E Churakova, T Quinto, ... Nature Chemistry 5 (2), 93-99, 2013 | 378 | 2013 |
A reductive aminase from Aspergillus oryzae GA Aleku, SP France, H Man, J Mangas-Sanchez, SL Montgomery, ... Nature chemistry 9 (10), 961-969, 2017 | 362 | 2017 |
Discovery, engineering, and synthetic application of transaminase biocatalysts I Slabu, JL Galman, RC Lloyd, NJ Turner ACS Catalysis 7 (12), 8263-8284, 2017 | 336 | 2017 |
Deracemization of α-methylbenzylamine using an enzyme obtained by in vitro evolution M Alexeeva, A Enright, MJ Dawson, M Mahmoudian, NJ Turner Angewandte Chemie-International Edition 41 (17), 3177-3180, 2002 | 318* | 2002 |
Cytochromes P450 as useful biocatalysts: addressing the limitations E O'Reilly, V Köhler, SL Flitsch, NJ Turner Chemical Communications 47 (9), 2490-2501, 2011 | 311 | 2011 |
Enantioselective oxidation of C–O and C–N bonds using oxidases NJ Turner Chemical reviews 111 (7), 4073-4087, 2011 | 290 | 2011 |
Enantioselective chemo‐and biocatalysis: partners in retrosynthesis M Hönig, P Sondermann, NJ Turner, EM Carreira Angewandte Chemie International Edition 56 (31), 8942-8973, 2017 | 289 | 2017 |
A chemo-enzymatic route to enantiomerically pure cyclic tertiary amines CJ Dunsmore, R Carr, T Fleming, NJ Turner Journal of the American Chemical Society 128 (7), 2224-2225, 2006 | 272 | 2006 |
Directed evolution of enzymes for applied biocatalysis NJ Turner TRENDS in Biotechnology 21 (11), 474-478, 2003 | 271 | 2003 |
Biocatalysis using immobilized enzymes in continuous flow for the synthesis of fine chemicals MP Thompson, I Peñafiel, SC Cosgrove, NJ Turner Organic process research & development 23 (1), 9-18, 2018 | 268 | 2018 |
Enzyme catalysed deracemisation and dynamic kinetic resolution reactions NJ Turner Current opinion in chemical biology 8 (2), 114-119, 2004 | 264 | 2004 |