| Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts AD Pfefferle, JI Herschkowitz, J Usary, JC Harrell, BT Spike, JR Adams, ... Genome biology 14, 1-16, 2013 | 252 | 2013 |
| Mutant PIK3CA accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapies AB Hanker, AD Pfefferle, JM Balko, MG Kuba, CD Young, V Sánchez, ... Proceedings of the National Academy of Sciences 110 (35), 14372-14377, 2013 | 209 | 2013 |
| Combined PI3K/mTOR and MEK inhibition provides broad antitumor activity in faithful murine cancer models PJ Roberts, JE Usary, DB Darr, PM Dillon, AD Pfefferle, MC Whittle, ... Clinical cancer research 18 (19), 5290-5303, 2012 | 168 | 2012 |
| LKB1/STK11 inactivation leads to expansion of a prometastatic tumor subpopulation in melanoma W Liu, KB Monahan, AD Pfefferle, T Shimamura, J Sorrentino, KT Chan, ... Cancer cell 21 (6), 751-764, 2012 | 146 | 2012 |
| Both noncoding and protein-coding RNAs contribute to gene expression evolution in the primate brain CC Babbitt, O Fedrigo, AD Pfefferle, AP Boyle, JE Horvath, TS Furey, ... Genome biology and evolution 2, 67-79, 2010 | 129 | 2010 |
| Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential J Knezevic, AD Pfefferle, I Petrovic, SB Greene, CM Perou, JM Rosen Oncogene 34 (49), 5997-6006, 2015 | 122 | 2015 |
| c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer R Nair, DL Roden, WS Teo, A McFarland, S Junankar, S Ye, A Nguyen, ... Oncogene 33 (30), 3992-4002, 2014 | 115 | 2014 |
| Oncogenic PI3K mutations lead to NF-κB–dependent cytokine expression following growth factor deprivation JE Hutti, AD Pfefferle, SC Russell, M Sircar, CM Perou, AS Baldwin Cancer research 72 (13), 3260-3269, 2012 | 92 | 2012 |
| Comparative Oncogenomics Implicates the Neurofibromin 1 Gene (NF1) as a Breast Cancer Driver MD Wallace, AD Pfefferle, L Shen, AJ McNairn, EG Cerami, BL Fallon, ... Genetics 192 (2), 385-396, 2012 | 83 | 2012 |
| Endothelial-like properties of claudin-low breast cancer cells promote tumor vascular permeability and metastasis JC Harrell, AD Pfefferle, N Zalles, A Prat, C Fan, A Khramtsov, OI Olopade, ... Clinical & experimental metastasis 31, 33-45, 2014 | 78 | 2014 |
| A potential role for glucose transporters in the evolution of human brain size O Fedrigo, AD Pfefferle, CC Babbitt, R Haygood, CE Wall, GA Wray Brain Behavior and Evolution 78 (4), 315-326, 2011 | 50 | 2011 |
| Comparative expression analysis of the phosphocreatine circuit in extant primates: implications for human brain evolution AD Pfefferle, LR Warner, CW Wang, WJ Nielsen, CC Babbitt, O Fedrigo, ... Journal of human evolution 60 (2), 205-212, 2011 | 47 | 2011 |
| Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells PD Rädler, BL Wehde, AA Triplett, H Shrestha, JH Shepherd, AD Pfefferle, ... Nature communications 12 (1), 3742, 2021 | 45 | 2021 |
| Overview of genetically engineered mouse models of distinct breast cancer subtypes J Usary, DB Darr, AD Pfefferle, CM Perou Current protocols in pharmacology 72 (1), 14.38. 1-14.38. 11, 2016 | 43 | 2016 |
| Ror2-mediated alternative Wnt signaling regulates cell fate and adhesion during mammary tumor progression K Roarty, AD Pfefferle, CJ Creighton, CM Perou, JM Rosen Oncogene 36 (43), 5958-5968, 2017 | 42 | 2017 |
| Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers AD Pfefferle, YN Agrawal, DC Koboldt, KL Kanchi, JI Herschkowitz, ... Disease models & mechanisms 9 (7), 749-757, 2016 | 41 | 2016 |
| Luminal progenitor and fetal mammary stem cell expression features predict breast tumor response to neoadjuvant chemotherapy AD Pfefferle, BT Spike, GM Wahl, CM Perou Breast cancer research and treatment 149, 425-437, 2015 | 38 | 2015 |
| Conditional loss of ErbB3 delays mammary gland hyperplasia induced by mutant PIK3CA without affecting mammary tumor latency, gene expression, or signaling CD Young, AD Pfefferle, P Owens, MG Kuba, BN Rexer, JM Balko, ... Cancer research 73 (13), 4075-4085, 2013 | 32 | 2013 |
| A pipeline to determine RT-QPCR control genes for evolutionary studies: application to primate gene expression across multiple tissues O Fedrigo, LR Warner, AD Pfefferle, CC Babbitt, P Cruz-Gordillo, GA Wray PLoS One 5 (9), e12545, 2010 | 28 | 2010 |
| A mouse model featuring tissue-specific deletion of p53 and Brca1 gives rise to mammary tumors with genomic and transcriptomic similarities to human basal-like breast cancer DP Hollern, CM Contreras, S Dance-Barnes, GO Silva, AD Pfefferle, ... Breast cancer research and treatment 174, 143-155, 2019 | 27 | 2019 |
