Giorgio Colombo

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Meli MassimilianoIstituto di Scienze e Tecnologie Chimiche (SCITEC-CNR)Verified email at scitec.cnr.it
Giulia MorraSCITEC CNRVerified email at scitec.cnr.it
Elisabetta MoroniIstituto di Scienze e Tecnologie Chimiche "Giulio Natta"- SCITEC CNRVerified email at scitec.cnr.it
Alessandro GoriIstituto di Chimica del Riconoscimento MolecolareVerified email at icrm.cnr.it
Claudio PeriIstituto Italiano di Tecnologia (IIT)Verified email at unimi.it
Stefano Artin SerapianUniversità degli Studi di PaviaVerified email at unipv.it
Dario AltieriProfessorVerified email at wistar.org
Andrea RasolaAssociate Professor, Università di Padova, ItaliaVerified email at unipd.it
Martino BolognesiProfessor of Biochemistry, University of MilanoVerified email at unimi.it
Laura RagonaIstituto di Scienze e Tecnologie Chimiche (SCITEC), CNRVerified email at scitec.cnr.it
Ilda D' AnnessaMedtronic EMEA - Study & Scientific Solutions Medtronic Clinical & Regulatory Solutions (MCRS)Verified email at medtronic.com
Taraboletti GIstituto di Ricerche Farmacologiche Mario Negri IRCCSVerified email at marionegri.it
Xavier DauraUNIVERSIDAD AUTONOMA DE BARCELONAVerified email at uab.cat
Guido TianaUniversity of MilanoVerified email at unimi.it
Marco NevesComputational Chemist, BIAL - Portela & Cª., S.A.Verified email at bial.com
Marina CretichNational Research Council of Italy, Istituto di Scienze e Tecnologie Chimiche (SCITEC-CNR)Verified email at icrm.cnr.it
Danilo RoccatanoSchool of Mathematics and Physics, University of Lincoln, Lincoln, UKVerified email at lincoln.ac.uk
Carlos Sanchez-MartinUniversità degli Studi di Bari - Research Fellow (grid.7644.1/ROR 027ynra39) - ITALYVerified email at usal.es
Silvia RinaldiICRM-CNRVerified email at icrm.cnr.it
Kenneth M. Merz Jr.University Distinguished Professor and Joseph Zichis Chair in Chemistry, Michigan State UniversityVerified email at msu.edu

Giorgio Colombo

Professor of Organic Chemistry, University of Pavia

Verified email at unipv.it - Homepage

Computational Biology Computational Chemistry Drug Design Protein Design Structural Vaccinology


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Mechanism by which 2, 2, 2-trifluoroethanol/water mixtures stabilize secondary-structure formation in peptides: a molecular dynamics study D Roccatano, G Colombo, M Fioroni, AE Mark Proceedings of the National Academy of Sciences 99 (19), 12179-12184, 2002	586	2002
Rational design of shepherdin, a novel anticancer agent J Plescia, W Salz, F Xia, M Pennati, N Zaffaroni, MG Daidone, M Meli, ... Cancer cell 7 (5), 457-468, 2005	407	2005
Structure-activity relationships of linear and cyclic peptides containing the NGR tumor-homing motif G Colombo, F Curnis, GMS De Mori, A Gasparri, C Longoni, A Sacchi, ... Journal of Biological Chemistry 277 (49), 47891-47897, 2002	249	2002
Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90 BH Kang, J Plescia, HY Song, M Meli, G Colombo, K Beebe, B Scroggins, ... The Journal of clinical investigation 119 (3), 454-464, 2009	244	2009
Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function M Mollapour, S Tsutsumi, AC Donnelly, K Beebe, MJ Tokita, MJ Lee, ... Molecular cell 37 (3), 333-343, 2010	187	2010
Peptide self-assembly at the nanoscale: a challenging target for computational and experimental biotechnology G Colombo, P Soto, E Gazit TRENDS in Biotechnology 25 (5), 211-218, 2007	173	2007
Modeling signal propagation mechanisms and ligand-based conformational dynamics of the Hsp90 molecular chaperone full-length dimer G Morra, G Verkhivker, G Colombo PLoS computational biology 5 (3), e1000323, 2009	163	2009
Solvent dynamics and mechanism of proton transfer in human carbonic anhydrase II S Toba, G Colombo, KM Merz Journal of the American Chemical Society 121 (10), 2290-2302, 1999	132	1999
The Chaperone TRAP1 As a Modulator of the Mitochondrial Adaptations in Cancer Cells I Masgras, C Sanchez-Martin, G Colombo, A Rasola Frontiers in Oncology 7, 58, 2017	114	2017
Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors B Gyurkocza, J Plescia, CM Raskett, DS Garlick, PA Lowry, BZ Carter, ... Journal of the National Cancer Institute 98 (15), 1068-1077, 2006	113	2006
β‐Hairpin conformation of fibrillogenic peptides: Structure and α‐β transition mechanism revealed by molecular dynamics simulations I Daidone, F Simona, D Roccatano, RA Broglia, G Tiana, G Colombo, ... Proteins: Structure, Function, and Bioinformatics 57 (1), 198-204, 2004	113	2004
Enantioselective Mukaiyama-Michael reactions of 2-carbomethoxy cyclopentenone catalyzed by chiral bis (oxazoline)-Cu (II) complexes A Bernardi, G Colombo, C Scolastico Tetrahedron letters 37 (49), 8921-8924, 1996	107	1996
Pharmacological enhancement of α-glucosidase by the allosteric chaperone N-acetylcysteine C Porto, MC Ferrara, M Meli, E Acampora, V Avolio, M Rosa, ... Molecular Therapy 20 (12), 2201-2211, 2012	106	2012
Small-molecule targeting of heat shock protein 90 chaperone function: rational identification of a new anticancer lead M Meli, M Pennati, M Curto, MG Daidone, J Plescia, S Toba, DC Altieri, ... Journal of medicinal chemistry 49 (26), 7721-7730, 2006	106	2006
Long-pentraxin 3 derivative as a small-molecule FGF trap for cancer therapy R Ronca, A Giacomini, E Di Salle, D Coltrini, K Pagano, L Ragona, ... Cancer cell 28 (2), 225-239, 2015	103	2015
Corresponding functional dynamics across the Hsp90 Chaperone family: insights from a multiscale analysis of MD simulations G Morra, R Potestio, C Micheletti, G Colombo PLoS computational biology 8 (3), e1002433, 2012	97	2012
Effect of hexafluoroisopropanol alcohol on the structure of melittin: A molecular dynamics simulation study D Roccatano, M Fioroni, M Zacharias, G Colombo Protein Science 14 (10), 2582-2589, 2005	96	2005
Sequence dependence of amyloid fibril formation: insights from molecular dynamics simulations ML de la Paz, GMS de Mori, L Serrano, G Colombo Journal of molecular biology 349 (3), 583-596, 2005	95	2005
Understanding the determinants of stability and folding of small globular proteins from their energetics G Tiana, F Simona, GMS De Mori, RA Broglia, G Colombo Protein Science 13 (1), 113-124, 2004	95	2004
Simulation of MscL gating in a bilayer under stress G Colombo, SJ Marrink, AE Mark Biophysical journal 84 (4), 2331-2337, 2003	95	2003

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